Endoglin antibody (AA 601-658) (AbBy Fluor® 750)

Catalog No. ABIN5608761

The Rabbit Polyclonal anti-Endoglin antibody has been validated for FACS, IF (cc) and IF (p). It is suitable to detect Endoglin in samples from Human and Rat.

Quick Overview for Endoglin antibody (AA 601-658) (AbBy Fluor® 750) (ABIN5608761)

Target: Endoglin (ENG)

Reactivity: Human, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Endoglin antibody is conjugated to AbBy Fluor® 750

Application: Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Product Details anti-Endoglin Antibody (AbBy Fluor® 750)

Binding Specificity: AA 601-658

Predicted Reactivity: Mouse,Dog,Cow,Pig,Horse,Chicken

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human CD105

Isotype: IgG

Application Details

Application Notes: FCM 1:20-100
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C/-80 °C

Storage Comment: Store at -20°C, for long storage, store at -80°C. Avoid multiple freeze-thaw cycles

Expiry Date: 12 months

Target Details for Endoglin

Target: Endoglin (ENG)

Alternative Name: CD105

Background:

Major glycoprotein of vascular endothelium. Involved in the regulation of angiogenesis. May play a critical role in the binding of endothelial cells to integrins and/or other RGD receptors. Acts as TGF-beta coreceptor and is involved in the TGF-beta/BMP signaling cascade. Required for GDF2/BMP9 signaling through SMAD1 in endothelial cells and modulates TGF-beta1 signaling through SMAD3.

Subcellular location: Cell membrane

Synonyms: END, HHT1, ORW1, Endoglin, CD15, ENG

Gene ID: 2022

UniProt: P17813