GGT1 antibody (AA 381-470)

Catalog No. ABIN561038

There are 4+ publications for this product available. The Mouse Monoclonal anti-GGT1 antibody is suitable to detect GGT1 in samples from Human. It has been validated for WB, ELISA, IP and IHC (p).

Quick Overview for GGT1 antibody (AA 381-470) (ABIN561038)

Target: GGT1 (gamma Glutamyltransferase 1 (GGT1))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This GGT1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: 1F9

Product Details anti-GGT1 Antibody

Binding Specificity: AA 381-470

Purpose: Mouse monoclonal antibody raised against a partial recombinant GGT1.

Sequence: TAHLSVVAED GSAVSATSTI NLYFGSKVRS PVSGILFNNE MDDFSSPSIT NEFGVPPSPA NFIQPGKQPL SSMCPTIMVG QDGQVRMVVG

Cross-Reactivity: Human, Mouse

Characteristics: Antibody Reactive Against Recombinant Protein.

Immunogen: GGT1 (NP_005256, 381 a.a. ~ 470 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Isotype: IgG2a

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: In 1x PBS, pH 7.4

Handling Advice: Aliquot to avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

References for anti-GGT1 antibody (ABIN561038)

Blackmore, Knisely, Hartley, McKay, Gissen, Marcus, Shawcross: "Polymorphisms in ABCB11 and ATP8B1 Associated with Development of Severe Intrahepatic Cholestasis in Hodgkin's Lymphoma." in: Journal of clinical and experimental hepatology, Vol. 3, Issue 2, pp. 159-61, (2015) (PubMed).

Grau, Luque-Garcia, González-Peramato, Theodorescu, Palou, Fernandez-Gomez, Sánchez-Carbayo: "A quantitative proteomic analysis uncovers the relevance of CUL3 in bladder cancer aggressiveness." in: PLoS ONE, Vol. 8, Issue 1, pp. e53328, (2013) (PubMed).

West, Wickham, Quinalty, Pavlovicz, Li, Hanigan: "Autocatalytic cleavage of human gamma-glutamyl transpeptidase is highly dependent on N-glycosylation at asparagine 95." in: The Journal of biological chemistry, Vol. 286, Issue 33, pp. 28876-88, (2011) (PubMed).

West, Segu, Feasley, Kang, Klouckova, Li, Novotny, West, Mechref, Hanigan: "Analysis of site-specific glycosylation of renal and hepatic ?-glutamyl transpeptidase from normal human tissue." in: The Journal of biological chemistry, Vol. 285, Issue 38, pp. 29511-24, (2010) (PubMed).

Target Details for GGT1

Target: GGT1 (gamma Glutamyltransferase 1 (GGT1))

Alternative Name: GGT1

Background: Full Gene Name: gamma-glutamyltransferase 1
Synonyms: CD224,D22S672,D22S732,GGT,GTG,MGC96892,MGC96904,MGC96963

Gene ID: 2678

NCBI Accession: NM_005265