Connexin 31 antibody (AA 1-270)

Catalog No. ABIN561044

There is 1 publication for this product available. The Mouse Monoclonal anti-Connexin 31 antibody is suitable to detect Connexin 31 in samples from Human. It has been validated for WB, ELISA and IF.

Quick Overview for Connexin 31 antibody (AA 1-270) (ABIN561044)

Target: Connexin 31 (GJB3) (Gap Junction Protein, beta 3, 31kDa (GJB3))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Connexin 31 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF)

Clone: 3B4-1B3

Product Details anti-Connexin 31 Antibody

Binding Specificity: AA 1-270

Purpose: Mouse monoclonal antibody raised against a full length recombinant GJB3.

Sequence: MDWKTLQALL SGVNKYSTAF GRIWLSVVFV FRVLVYVVAA ERVWGDEQKD FDCNTKQPGC TNVCYDNYFP ISNIRLWALQ LIFVTCPSLL VILHVAYREE RERRHRQKHG DQCAKLYDNA GKKHGGLWWT YLFSLIFKLI IEFLFLYLLH TLWHGFNMPR LVQCANVAPC PNIVDCYIAR PTEKKIFTYF MVGASAVCIV LTICELCYLI CHRVLRGLHK DKPRGGCSPS SSASRASTCR CHHKLVEAGE VDPDPGNNKL QASAPNLTPI

Cross-Reactivity: Human

Characteristics: Antibody Reactive Against Recombinant Protein.

Immunogen: GJB3 (AAH12918.1, 1 a.a. ~ 270 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Isotype: IgG1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: In 1x PBS, pH 7.4

Handling Advice: Aliquot to avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

References for anti-Connexin 31 antibody (ABIN561044)

Tattersall, Scott, Gray, Zicha, Kelsell: "EKV mutant connexin 31 associated cell death is mediated by ER stress." in: Human molecular genetics, Vol. 18, Issue 24, pp. 4734-45, (2009) (PubMed).

Target Details for Connexin 31

Target: Connexin 31 (GJB3) (Gap Junction Protein, beta 3, 31kDa (GJB3))

Alternative Name: GJB3

Background: Full Gene Name: gap junction protein, beta 3, 31 kDa
Synonyms: CX31,DFNA2,EKV,FLJ22486,MGC102938

Gene ID: 2707

Pathways: Sensory Perception of Sound