Endothelin 1 antibody (C-Term)

Catalog No. ABIN5610818

The Mouse Monoclonal anti-Endothelin 1 antibody (Clone IC4) (ABIN5610818) specifically detects Endothelin 1 in RIA, IHC (fro), EIA and ELISA (Capture). The antibody is reactive with Human samples.

Quick Overview for Endothelin 1 antibody (C-Term) (ABIN5610818)

Target: Endothelin 1 (EDN1)

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Endothelin 1 antibody is un-conjugated

Application: Radioimmunoassay (RIA), Immunohistochemistry (Frozen Sections) (IHC (fro)), Enzyme Immunoassay (EIA), ELISA (Capture)

Clone: IC4

Product Details anti-Endothelin 1 Antibody

Binding Specificity: C-Term

Specificity: This antibody recognizes Endothelin 1 (100 %) and shows < 10 % reactivity with Endothelin 3.Aff. Const.:4 x 1010

Purification: Affinity chromatography on Protein A

Immunogen: Synthetic Human Endothelin-1 C-Terminal fragment

Isotype: IgG1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 1,0 mg/mL (OD280nm)

Buffer: PBS, pH 7.2 containing 10 mM Sodium azide as preservative

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for Endothelin 1

Target: Endothelin 1 (EDN1)

Alternative Name: Endothelin-1

Background: Synonyms: EDN1, ET1, HDLCQ7, PPET1, Preproendothelin-1

Gene ID: 1906

NCBI Accession: NP_001161791

UniProt: P05305

Pathways: Hormone Transport, Negative Regulation of Hormone Secretion, Regulation of Systemic Arterial Blood Pressure by Hormones, cAMP Metabolic Process, Regulation of Muscle Cell Differentiation, Regulation of G-Protein Coupled Receptor Protein Signaling, Regulation of Cell Size