14-3-3 sigma/SFN antibody (AA 1-248)

Catalog No. ABIN561091

This Mouse Monoclonal antibody specifically detects 14-3-3 sigma/SFN in WB, ELISA, IP and IHC (p). It exhibits reactivity toward Humanand has been mentioned in 1 publication.

Quick Overview for 14-3-3 sigma/SFN antibody (AA 1-248) (ABIN561091)

Target: 14-3-3 sigma/SFN (SFN) (Stratifin (SFN))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This 14-3-3 sigma/SFN antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: 3C3

Product Details anti-14-3-3 sigma/SFN Antibody

Binding Specificity: AA 1-248

Purpose: Mouse monoclonal antibody raised against a full length recombinant SFN.

Sequence: MERASLIQKA KLAEQAERYE DMAAFMKGAV EKGEELSCEE RNLLSVAYKN VVGGQRAAWR VLSSIEQKSN EEGSEEKGPE VREYREKAET ELQGVCDTVL GLLDSHLIKE AGDAESRVFY LKMKGDYYRY LAEVATGDDK KRIIDSARSA YQEAMDISKK EMPPTNPIRL GLALNFSVFH YEIANSPEEA ISLAKTTFDE AMADLHTLSE DSYKDSTLIM QLLRDNLTLW TADNAGEEGG EAPQEPQS

Cross-Reactivity: Human

Characteristics: Antibody Reactive Against Recombinant Protein.

Immunogen: SFN (AAH00329.1, 1 a.a. ~ 248 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Isotype: IgG1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: In 1x PBS, pH 7.4

Handling Advice: Aliquot to avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

References for anti-14-3-3 sigma/SFN antibody (ABIN561091)

Sousa, Zub, Aas, Hanssen-Bauer, Demirovic, Sarno, Tian, Liabakk, Slupphaug: "An inverse switch in DNA base excision and strand break repair contributes to melphalan resistance in multiple myeloma cells." in: PLoS ONE, Vol. 8, Issue 2, pp. e55493, (2013) (PubMed).

Target Details for 14-3-3 sigma/SFN

Target: 14-3-3 sigma/SFN (SFN) (Stratifin (SFN))

Alternative Name: SFN

Background: Full Gene Name: stratifin
Synonyms: YWHAS

Gene ID: 2810

Pathways: p53 Signaling, Myometrial Relaxation and Contraction