TNFRSF4 antibody (AA 29-214)
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- Target See all TNFRSF4 Antibodies
- TNFRSF4 (Tumor Necrosis Factor Receptor Superfamily, Member 4 (TNFRSF4))
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Binding Specificity
- AA 29-214
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Reactivity
- Human
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This TNFRSF4 antibody is un-conjugated
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Application
- ELISA
- Purpose
- OX40 Antibody
- Purification
- Purified antibody
- Immunogen
- Purified recombinant fragment of human OX40 (AA: 29-214) expressed in HEK293 cells.
- Clone
- 7B5E10
- Isotype
- IgG2a
- Top Product
- Discover our top product TNFRSF4 Primary Antibody
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- Application Notes
- ELISA: 1/10000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Purified antibody in PBS with 0.05 % sodium azide.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C,-20 °C
- Storage Comment
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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- Target
- TNFRSF4 (Tumor Necrosis Factor Receptor Superfamily, Member 4 (TNFRSF4))
- Alternative Name
- OX40 (TNFRSF4 Products)
- Background
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Description: The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor has been shown to activate NF-kappaB through its interaction with adaptor proteins TRAF2 and TRAF5. Knockout studies in mice suggested that this receptor promotes the expression of apoptosis inhibitors BCL2 and BCL2lL1/BCL2-XL, and thus suppresses apoptosis. The knockout studies also suggested the roles of this receptor in CD4+ T cell response, as well as in T cell-dependent B cell proliferation and differentiation.
Aliases: TNFRSF4, ACT35, CD134, IMD16, TXGP1L
- Molecular Weight
- 29.3kDa
- Gene ID
- 7293
- HGNC
- 7293
- UniProt
- P43489
- Pathways
- Production of Molecular Mediator of Immune Response, Cancer Immune Checkpoints
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