DDR1 antibody (AA 21-176)

Catalog No. ABIN5611283

This Mouse Monoclonal antibody specifically detects DDR1 in ELISA and FACS. It exhibits reactivity toward Human.

Quick Overview for DDR1 antibody (AA 21-176) (ABIN5611283)

Target: DDR1 (Discoidin Domain Receptor tyrosine Kinase 1 (DDR1))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This DDR1 antibody is un-conjugated

Application: ELISA, Flow Cytometry (FACS)

Clone: 4F2C12

Product Details anti-DDR1 Antibody

Binding Specificity: AA 21-176

Purpose: CD167 Antibody

Purification: Purified antibody

Immunogen: Purified recombinant fragment of human CD167 (AA: 21-176) expressed in E. Coli.

Isotype: IgG2b

Application Details

Application Notes:

ELISA: 1/10000

FCM: 1/200 - 1/400

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Target Details for DDR1

Target: DDR1 (Discoidin Domain Receptor tyrosine Kinase 1 (DDR1))

Alternative Name: CD167

Background: Receptor tyrosine kinases play a key role in the communication of cells with their microenvironment. These kinases are involved in the regulation of cell growth, differentiation and metabolism. The protein encoded by this gene belongs to a subfamily of tyrosine kinase receptors with homology to Dictyostelium discoideum protein discoidin I in their extracellular domain, and that are activated by various types of collagen. Expression of this protein is restricted to epithelial cells, particularly in the kidney, lung, gastrointestinal tract, and brain. In addition, it has been shown to be significantly overexpressed in several human tumors. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.

Molecular Weight: 101 kDa

UniProt: Q08345

Pathways: RTK Signaling, Smooth Muscle Cell Migration