HIP1 antibody (AA 928-1037)

Catalog No. ABIN561262

This Mouse Polyclonal antibody specifically detects HIP1 in WB and ELISA. It exhibits reactivity toward Human. It has been mentioned in 6+ publications

Quick Overview for HIP1 antibody (AA 928-1037) (ABIN561262)

Target: HIP1 (Huntingtin Interacting Protein 1 (HIP1))

Reactivity: Human

Host: Mouse

Clonality: Polyclonal

Conjugate: This HIP1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-HIP1 Antibody

Binding Specificity: AA 928-1037

Purpose: Mouse polyclonal antibody raised against a partial recombinant HIP1.

Sequence: DSPNLAQLQQ ASRGVNQATA GVVASTISGK SQIEETDNMD FSSMTLTQIK RQEMDSQVRV LELENELQKE RQKLGELRKK HYELAGVAEG WEEGTEASPP TLQEVVTEKE

Cross-Reactivity: Human

Characteristics: Antibody Reactive Against Recombinant Protein.

Immunogen: HIP1 (NP_005329, 928 a.a. ~ 1037 a.a) partial recombinant protein with GST tag.

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: 50 % glycerol

Handling Advice: Aliquot to avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

References for anti-HIP1 antibody (ABIN561262)

Peng: "The T-box transcription factor T-bet in immunity and autoimmunity." in: Cellular & molecular immunology, Vol. 3, Issue 2, pp. 87-95, (2006) (PubMed).

Hwang, Hong, Glimcher: "IL-2 production in developing Th1 cells is regulated by heterodimerization of RelA and T-bet and requires T-bet serine residue 508." in: The Journal of experimental medicine, Vol. 202, Issue 9, pp. 1289-300, (2005) (PubMed).

Hwang, Szabo, Schwartzberg, Glimcher: "T helper cell fate specified by kinase-mediated interaction of T-bet with GATA-3." in: Science (New York, N.Y.), Vol. 307, Issue 5708, pp. 430-3, (2005) (PubMed).

Hibbert, Pflanz, De Waal Malefyt, Kastelein: "IL-27 and IFN-alpha signal via Stat1 and Stat3 and induce T-Bet and IL-12Rbeta2 in naive T cells." in: Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research, Vol. 23, Issue 9, pp. 513-22, (2003) (PubMed).

Peng, Szabo, Glimcher: "T-bet regulates IgG class switching and pathogenic autoantibody production." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 99, Issue 8, pp. 5545-50, (2002) (PubMed).

Szabo, Kim, Costa, Zhang, Fathman, Glimcher: "A novel transcription factor, T-bet, directs Th1 lineage commitment." in: Cell, Vol. 100, Issue 6, pp. 655-69, (2000) (PubMed).

Target Details for HIP1

Target: HIP1 (Huntingtin Interacting Protein 1 (HIP1))

Alternative Name: HIP1

Background: Full Gene Name: huntingtin interacting protein 1
Synonyms: ILWEQ,MGC126506

Gene ID: 3092

NCBI Accession: NM_005338

Pathways: Positive Regulation of Endopeptidase Activity