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K-RAS antibody (AA 16-125)

This Mouse Monoclonal antibody specifically detects K-RAS in WB and ELISA. It exhibits reactivity toward Humanand has been mentioned in 1 publication.
Catalog No. ABIN561622

Quick Overview for K-RAS antibody (AA 16-125) (ABIN561622)

Target

See all K-RAS (KRAS) Antibodies
K-RAS (KRAS) (GTPase Kras (KRAS))

Reactivity

  • 74
  • 39
  • 32
  • 5
  • 4
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
Human

Host

  • 75
  • 11
Mouse

Clonality

  • 74
  • 12
Monoclonal

Conjugate

  • 44
  • 7
  • 4
  • 4
  • 3
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This K-RAS antibody is un-conjugated

Application

  • 74
  • 35
  • 23
  • 16
  • 15
  • 14
  • 14
  • 8
  • 7
  • 7
  • 4
  • 1
Western Blotting (WB), ELISA

Clone

4F3
  • Binding Specificity

    • 16
    • 10
    • 8
    • 7
    • 6
    • 6
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 16-125

    Purpose

    Mouse monoclonal antibody raised against a partial recombinant KRAS.

    Sequence

    KSALTIQLIQ NHFVDEYDPT IEDSYRKQVV IDGETCLLDI LDTAGQEEYS AMRDQYMRTG EGFLCVFAIN NTKSFEDIHH YREQIKRVKD SEDVPMVLVG NKCDLPSRTV

    Cross-Reactivity

    Human

    Characteristics

    Antibody Reactive Against Recombinant Protein.

    Immunogen

    KRAS (NP_004976, 16 a.a. ~ 125 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

    Isotype

    IgG2a
  • Application Notes

    Optimal working dilution should be determined by the investigator.

    Restrictions

    For Research Use only
  • Buffer

    In 1x PBS, pH 7.4

    Handling Advice

    Aliquot to avoid repeated freezing and thawing.

    Storage

    -20 °C

    Storage Comment

    Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
  • Mologni, Brussolo, Ceccon, Gambacorti-Passerini: "Synergistic effects of combined Wnt/KRAS inhibition in colorectal cancer cells." in: PLoS ONE, Vol. 7, Issue 12, pp. e51449, (2012) (PubMed).

  • Target

    K-RAS (KRAS) (GTPase Kras (KRAS))

    Alternative Name

    KRAS

    Background

    Full Gene Name: v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog
    Synonyms: C-K-RAS,K-RAS2A,K-RAS2B,K-RAS4A,K-RAS4B,KI-RAS,KRAS1,KRAS2,NS3,RASK2

    Gene ID

    3845

    NCBI Accession

    NM_004985
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