K-RAS antibody (AA 16-125)
Quick Overview for K-RAS antibody (AA 16-125) (ABIN561622)
Target
See all K-RAS (KRAS) AntibodiesReactivity
Host
Clonality
Conjugate
Application
Clone
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Binding Specificity
- AA 16-125
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Purpose
- Mouse monoclonal antibody raised against a partial recombinant KRAS.
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Sequence
- KSALTIQLIQ NHFVDEYDPT IEDSYRKQVV IDGETCLLDI LDTAGQEEYS AMRDQYMRTG EGFLCVFAIN NTKSFEDIHH YREQIKRVKD SEDVPMVLVG NKCDLPSRTV
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Cross-Reactivity
- Human
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Characteristics
- Antibody Reactive Against Recombinant Protein.
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Immunogen
- KRAS (NP_004976, 16 a.a. ~ 125 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
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Isotype
- IgG2a
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Buffer
- In 1x PBS, pH 7.4
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Handling Advice
- Aliquot to avoid repeated freezing and thawing.
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Storage
- -20 °C
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Storage Comment
- Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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: "Synergistic effects of combined Wnt/KRAS inhibition in colorectal cancer cells." in: PLoS ONE, Vol. 7, Issue 12, pp. e51449, (2012) (PubMed).
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: "Synergistic effects of combined Wnt/KRAS inhibition in colorectal cancer cells." in: PLoS ONE, Vol. 7, Issue 12, pp. e51449, (2012) (PubMed).
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- K-RAS (KRAS) (GTPase Kras (KRAS))
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Alternative Name
- KRAS
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Background
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Full Gene Name: v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog
Synonyms: C-K-RAS,K-RAS2A,K-RAS2B,K-RAS4A,K-RAS4B,KI-RAS,KRAS1,KRAS2,NS3,RASK2 -
Gene ID
- 3845
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NCBI Accession
- NM_004985
Target
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