LDLR antibody (AA 105-205)

Catalog No. ABIN561655

This Mouse Monoclonal antibody specifically detects LDLR in WB and ELISA. It exhibits reactivity toward Humanand has been mentioned in 1 publication.

Quick Overview for LDLR antibody (AA 105-205) (ABIN561655)

Target: LDLR (Low Density Lipoprotein Receptor (LDLR))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This LDLR antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Clone: 5E7

Product Details anti-LDLR Antibody

Binding Specificity: AA 105-205

Purpose: Mouse monoclonal antibody raised against a partial recombinant LDLR.

Sequence: PPKTCSQDEF RCHDGKCISR QFVCDSDRDC LDGSDEASCP VLTCGPASFQ CNSSTCIPQL WACDNDPDCE DGSDEWPQRC RGLYVFQGDS SPCSAFEFHC L

Cross-Reactivity: Human

Characteristics: Antibody Reactive Against Recombinant Protein.

Immunogen: LDLR (NP_000518, 105 a.a. ~ 205 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Isotype: IgG2a

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: In 1x PBS, pH 7.4

Handling Advice: Aliquot to avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

References for anti-LDLR antibody (ABIN561655)

Ueno, Wu, Nakagawa, Nagai, Onodera, Huang, Kusaka, Kanenishi, Sakamoto: "The expression of LDL receptor in vessels with blood-brain barrier impairment in a stroke-prone hypertensive model." in: Histochemistry and cell biology, Vol. 133, Issue 6, pp. 669-76, (2010) (PubMed).

Target Details for LDLR

Target: LDLR (Low Density Lipoprotein Receptor (LDLR))

Alternative Name: LDLR

Background: Full Gene Name: low density lipoprotein receptor
Synonyms: FH,FHC

Gene ID: 3949

NCBI Accession: NM_000527

Pathways: Hepatitis C, Lipid Metabolism