RPS6KB1 antibody (Thr229)

Catalog No. ABIN5618510

This Rabbit Polyclonal antibody specifically detects RPS6KB1 in WB, IHC, ELISA and IF. It exhibits reactivity toward Humanand has been mentioned in 1 publication.

Quick Overview for RPS6KB1 antibody (Thr229) (ABIN5618510)

Target: RPS6KB1 (Ribosomal Protein S6 Kinase, 70kDa, Polypeptide 1 (RPS6KB1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RPS6KB1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Product Details anti-RPS6KB1 Antibody

Binding Specificity: Thr229

Specificity: P70S6k antibody detects endogenous levels of total p70S6k protein

Cross-Reactivity (Details): Mouse, Rat

Characteristics: Rabbit polyclonal p70S6k antibody

Purification: p70S6k antibody was purified by affinity chromatography

Immunogen: p70S6k antibody was raised in Rabbit using a synthesized non-phosphopeptide derived from human p70S6k around the phosphorylation site of threonine 229 (T-H-TP-F-C) as the immunogen

Isotype: IgG

Application Details

Application Notes: WB: 1:500 - 1:1000, IHC: 1:50 - 1:100, IF: 1:100 - 1:500, ELISA: 1:40000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Supplied in liquid format, PBS buffer, pH 7.4, 150 mM NaCl with added preservative 0.02 % sodium azide and 50 % glycerol

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot and store at -20 deg C. Avoid repeated freeze thaw cycles

References for anti-RPS6KB1 antibody (ABIN5618510)

Guo, Liu, Bow, Cui, Zhang, Xu, Lu, Tian: "The protective effect and mechanism of rapamycin in the rat model of IgA nephropathy." in: Renal failure, Vol. 41, Issue 1, pp. 334-339, (2019) (PubMed).

Target Details for RPS6KB1

Target: RPS6KB1 (Ribosomal Protein S6 Kinase, 70kDa, Polypeptide 1 (RPS6KB1))

Alternative Name: p70S6k

Pathways: PI3K-Akt Signaling, RTK Signaling, AMPK Signaling, Regulation of Cell Size, Skeletal Muscle Fiber Development, Feeding Behaviour, G-protein mediated Events, Smooth Muscle Cell Migration, Interaction of EGFR with phospholipase C-gamma, Warburg Effect