PAK1 antibody (AA 191-280)

Catalog No. ABIN562102

This Mouse Monoclonal antibody specifically detects PAK1 in WB, ELISA, IF, IHC (p) and IP. It exhibits reactivity toward Humanand has been mentioned in 1 publication.

Quick Overview for PAK1 antibody (AA 191-280) (ABIN562102)

Target: PAK1 (P21-Activated Kinase 1 (PAK1))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This PAK1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP)

Clone: 4D1

Product Details anti-PAK1 Antibody

Binding Specificity: AA 191-280

Purpose: Mouse monoclonal antibody raised against a partial recombinant PAK1.

Sequence: APRPEHTKSV YTRSVIEPLP VTPTRDVATS PISPTENNTT PPDALTRNTE KQKKKPKMSD EEILEKLRSI VSVGDPKKKY TRFEKIGQGA

Cross-Reactivity: Human

Characteristics: Antibody Reactive Against Recombinant Protein.

Immunogen: PAK1 (NP_002567, 191 a.a. ~ 280 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Isotype: IgG1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: In 1x PBS, pH 7.4

Handling Advice: Aliquot to avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

References for anti-PAK1 antibody (ABIN562102)

Cook, Sanchez-Carbente, Lachance, Radzioch, Tremblay, Khandjian, DesGroseillers, Murai: "Fragile X related protein 1 clusters with ribosomes and messenger RNAs at a subset of dendritic spines in the mouse hippocampus." in: PLoS ONE, Vol. 6, Issue 10, pp. e26120, (2011) (PubMed).

Target Details for PAK1

Target: PAK1 (P21-Activated Kinase 1 (PAK1))

Alternative Name: PAK1

Background: Full Gene Name: p21 protein (Cdc42/Rac)-activated kinase 1
Synonyms: MGC130000,MGC130001,PAKalpha

Gene ID: 5058

NCBI Accession: NM_002576

Pathways: MAPK Signaling, RTK Signaling, TCR Signaling, Fc-epsilon Receptor Signaling Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Skeletal Muscle Fiber Development, CXCR4-mediated Signaling Events, Signaling Events mediated by VEGFR1 and VEGFR2, Signaling of Hepatocyte Growth Factor Receptor, Embryonic Body Morphogenesis