PDE1B antibody (AA 437-536)

Catalog No. ABIN562152

Cited in 1 publication. The Mouse Monoclonal anti-PDE1B antibody (Clone 5B6) (ABIN562152) specifically detects PDE1B in WB and ELISA. The antibody is reactive with Human samples.

Quick Overview for PDE1B antibody (AA 437-536) (ABIN562152)

Target: PDE1B (phosphodiesterase 1B, Calmodulin-Dependent (PDE1B))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This PDE1B antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Clone: 5B6

Product Details anti-PDE1B Antibody

Binding Specificity: AA 437-536

Purpose: Mouse monoclonal antibody raised against a partial recombinant PDE1B.

Sequence: TDVAEKSVQP LADEDSKSKN QPSFQWRQPS LDVEVGDPNP DVVSFRSTWV KRIQENKQKW KERAASGITN QMSIDELSPC EEEAPPSPAE DEHNQNGNLD

Cross-Reactivity: Human

Characteristics: Antibody Reactive Against Recombinant Protein.

Immunogen: PDE1B (AAH32226, 437 a.a. ~ 536 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Isotype: IgG2a

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: In 1x PBS, pH 7.4

Handling Advice: Aliquot to avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

References for anti-PDE1B antibody (ABIN562152)

Bazhin, Kahnert, Kimpfler, Schadendorf, Umansky: "Distinct metabolism of cyclic adenosine monophosphate in regulatory and helper CD4+ T cells." in: Molecular immunology, Vol. 47, Issue 4, pp. 678-84, (2010) (PubMed).

Target Details for PDE1B

Target: PDE1B (phosphodiesterase 1B, Calmodulin-Dependent (PDE1B))

Alternative Name: PDE1B

Background: Full Gene Name: phosphodiesterase 1B, calmodulin-dependent
Synonyms: PDE1B1,PDES1B

Gene ID: 5153

Pathways: Neurotrophin Signaling Pathway, cAMP Metabolic Process, G-protein mediated Events, Interaction of EGFR with phospholipase C-gamma