TPT1 antibody (AA 35-138)

Catalog No. ABIN563247

Cited in 2+ publications. The Mouse Monoclonal anti-TPT1 antibody (Clone 3C7) (ABIN563247) specifically detects TPT1 in WB, ELISA and IF. The antibody is reactive with Human samples.

Quick Overview for TPT1 antibody (AA 35-138) (ABIN563247)

Target: TPT1 (Tumor Protein, Translationally-Controlled 1 (TPT1))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This TPT1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF)

Clone: 3C7

Product Details anti-TPT1 Antibody

Binding Specificity: AA 35-138

Purpose: Mouse monoclonal antibody raised against a partial recombinant TPT1.

Sequence: GVDIVMNHHL QETSFTKEAY KKYIKDYMKS IKGKLEEQRP ERVKPFMTGA AEQIKHILAN FKNYQFFIGE NMNPDGMVAL LDYREDGVTP YMIFFKDGLE MEKC

Cross-Reactivity: Human

Characteristics: Antibody Reactive Against Recombinant Protein.

Immunogen: TPT1 (AAH22436, 35 a.a. ~ 138 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Isotype: IgG1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: In 1x PBS, pH 7.4

Handling Advice: Aliquot to avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

References for anti-TPT1 antibody (ABIN563247)

Chen, Huang, Yuan, Cheng, Zhou: "Long-term artificial selection reveals a role of TCTP in autophagy in mammalian cells." in: Molecular biology and evolution, Vol. 31, Issue 8, pp. 2194-211, (2014) (PubMed).

Chen, Chen, Huang, Cheng, Zhou: "TCTP increases stability of hypoxia-inducible factor 1? by interaction with and degradation of the tumour suppressor VHL." in: Biology of the cell / under the auspices of the European Cell Biology Organization, Vol. 105, Issue 5, pp. 208-18, (2013) (PubMed).

Target Details for TPT1

Target: TPT1 (Tumor Protein, Translationally-Controlled 1 (TPT1))

Alternative Name: TPT1

Background: Full Gene Name: tumor protein, translationally-controlled 1
Synonyms: FLJ27337,HRF,TCTP,p02

Gene ID: 7178

Pathways: Response to Water Deprivation, Regulation of Cell Size, Negative Regulation of intrinsic apoptotic Signaling