TPT1 antibody (AA 85-172)

Catalog No. ABIN701080

This Rabbit Polyclonal antibody specifically detects TPT1 in WB, IF (cc), IF (p), IHC (p) and IHC (fro). It exhibits reactivity toward Human. It has been mentioned in 2+ publications

Quick Overview for TPT1 antibody (AA 85-172) (ABIN701080)

Target: TPT1 (Tumor Protein, Translationally-Controlled 1 (TPT1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TPT1 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-TPT1 Antibody

Binding Specificity: AA 85-172

Purpose: TCTP Polyclonal Antibody

Cross-Reactivity: Human, Mouse

Predicted Reactivity: Rat,Dog,Cow,Sheep,Pig,Horse,Rabbit,GuineaPig

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human TCTP

Isotype: IgG

Application Details

Application Notes: WB(1:300-5000),

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

References for anti-TPT1 antibody (ABIN701080)

Wu, Guo, Min, Zhou, Li, Li, Luo: "Upregulation of TCTP expression in human skin squamous cell carcinoma increases tumor cell viability through anti-apoptotic action of the protein." in: Experimental and therapeutic medicine, Vol. 3, Issue 3, pp. 437-442, (2012) (PubMed).

Target Details for TPT1

Target: TPT1 (Tumor Protein, Translationally-Controlled 1 (TPT1))

Alternative Name: TCTP

Background:

Synonyms: FLJ27337, Fortilin, Histamine releasing factor, Histamine-releasing factor, HRF, Immunoglobulin E-dependent, p02, p23, TCTP, TCTP_HUMAN, TPT1, Translationally controlled tumor protein, Translationally-controlled tumor protein, Tumor protein translationally controlled 1, tumor protein translationally-controlled 1, tumor protein, translationally-controlled 1.

Background: TCTP is involved in calcium binding and microtubule stabilization. It is an immunoglobulin E dependent histamine-releasing factor produced by lymphocytes of atopic children and present in biologic fluids of allergic patients. Both human and mouse recombinant HRF proteins caused histamine release from human basophils of a subpopulation of donors (referenced from OMIM).

Gene ID: 7178

Pathways: Response to Water Deprivation, Regulation of Cell Size, Negative Regulation of intrinsic apoptotic Signaling