MED17 antibody (AA 551-651)

Catalog No. ABIN564067

This Mouse Monoclonal antibody specifically detects MED17 in WB, ELISA, IF and IHC (p). It exhibits reactivity toward Human and has been mentioned in 2+ publications.

Quick Overview for MED17 antibody (AA 551-651) (ABIN564067)

Target: MED17 (Mediator Complex Subunit 17 (MED17))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This MED17 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: 4D4

Product Details anti-MED17 Antibody

Binding Specificity: AA 551-651

Purpose: Mouse monoclonal antibody raised against a partial recombinant CRSP6.

Sequence: FSNHVGLGPI ESIGNASAIT VASPSGDYAI SVRNGPESGS KIMVQFPRNQ CKDLPKSDVL QDNKWSHLRG PFKEVQWNKM EGRNFVYKME LLMSALSPCL L

Cross-Reactivity: Human

Characteristics: Antibody Reactive Against Recombinant Protein.

Immunogen: CRSP6 (AAH21101, 551 a.a. ~ 651 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Isotype: IgG1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: In 1x PBS, pH 7.4

Handling Advice: Aliquot to avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

References for anti-MED17 antibody (ABIN564067)

Kikuchi, Umemura, Nishitani, Iida, Fukasawa, Hayashi, Hirose, Tanaka, Sugasawa, Ohkuma: "Human mediator MED17 subunit plays essential roles in gene regulation by associating with the transcription and DNA repair machineries." in: Genes to cells : devoted to molecular & cellular mechanisms, Vol. 20, Issue 3, pp. 191-202, (2015) (PubMed).

Tsutsui, Fukasawa, Tanaka, Hirose, Ohkuma: "Identification of target genes for the CDK subunits of the Mediator complex." in: Genes to cells : devoted to molecular & cellular mechanisms, (2011) (PubMed).

Target Details for MED17

Target: MED17 (Mediator Complex Subunit 17 (MED17))

Alternative Name: MED17

Background: Full Gene Name: mediator complex subunit 17
Synonyms: CRSP6,CRSP77,DRIP80,FLJ10812,TRAP80

Gene ID: 9440

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway, Stem Cell Maintenance, Regulation of Lipid Metabolism by PPARalpha