MED12 antibody (AA 1829-1941)

Catalog No. ABIN564287

There are 2+ publications for this product available. The Mouse Polyclonal anti-MED12 antibody is suitable to detect MED12 in samples from Human. It has been validated for ELISA and WB.

Quick Overview for MED12 antibody (AA 1829-1941) (ABIN564287)

Target: MED12 (Mediator Complex Subunit 12 (MED12))

Reactivity: Human

Host: Mouse

Clonality: Polyclonal

Conjugate: This MED12 antibody is un-conjugated

Application: ELISA, Western Blotting (WB)

Product Details anti-MED12 Antibody

Binding Specificity: AA 1829-1941

Purpose: Mouse polyclonal antibody raised against a partial recombinant MED12.

Sequence: QPATKTEDYG MGPGRSGPYG VTVPPDLLHH PNPGSITHLN YRQGSIGLYT QNQPLPAGGP RVDPYRPVRL PMQKLPTRPT YPGVLPTTMT GVMGLEPSSY KTSVYRQQQP AVP

Cross-Reactivity: Human

Characteristics: Antibody Reactive Against Recombinant Protein.

Immunogen: MED12 (NP_005111, 1829 a.a. ~ 1941 a.a) partial recombinant protein with GST tag.

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: 50 % glycerol

Handling Advice: Aliquot to avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

References for anti-MED12 antibody (ABIN564287)

Shen, Szewczyk, Eram, Smil, Kaniskan, de Freitas, Senisterra, Li, Schapira, Brown, Arrowsmith, Barsyte-Lovejoy, Liu, Vedadi, Jin: "Discovery of a Potent, Selective, and Cell-Active Dual Inhibitor of Protein Arginine Methyltransferase 4 and Protein Arginine Methyltransferase 6." in: Journal of medicinal chemistry, Vol. 59, Issue 19, pp. 9124-9139, (2016) (PubMed).

Rienzo, Casamassimi, Schiano, Grimaldi, Infante, Napoli: "Distinct alternative splicing patterns of mediator subunit genes during endothelial progenitor cell differentiation." in: Biochimie, Vol. 94, Issue 8, pp. 1828-32, (2012) (PubMed).

Target Details for MED12

Target: MED12 (Mediator Complex Subunit 12 (MED12))

Alternative Name: MED12

Background: Full Gene Name: mediator complex subunit 12
Synonyms: CAGH45,FGS1,HOPA,KIAA0192,OKS,OPA1,TNRC11,TRAP230

Gene ID: 9968

NCBI Accession: NM_005120

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway, Nuclear Hormone Receptor Binding, Stem Cell Maintenance, Chromatin Binding, Regulation of Lipid Metabolism by PPARalpha, Tube Formation