Dynamin 1-Like antibody (AA 1-710)

Catalog No. ABIN564347

The Mouse Monoclonal anti-Dynamin 1-Like antibody has been validated for WB, ELISA and IHC (p). It is suitable to detect Dynamin 1-Like in samples from Human. There are 4+ publications available.

Quick Overview for Dynamin 1-Like antibody (AA 1-710) (ABIN564347)

Target: Dynamin 1-Like (DNM1L)

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Dynamin 1-Like antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: 3B5

Product Details anti-Dynamin 1-Like Antibody

Binding Specificity: AA 1-710

Purpose: Mouse monoclonal antibody raised against a full length recombinant DNM1L.

Sequence: MEALIPVINK LQDVFNTVGA DIIQLPQIVV VGTQSSGKSS VLESLVGRDL LPRGTGIVTR RPLILQLVHV SQEDKRKTTG EENGVEAEEW GKFLHTKNKL YTDFDEIRQE IENETERISG NNKGVSPEPI HLKIFSPNVV NLTLVDLPGM TKVPVGDQPK DIELQIRELI LRFISNPNSI ILAVTAANTD MATSEALKIS REVDPDGRRT LAVITKLDLM DAGTDAMDVL MGRVIPVKLG IIGVVNRSQL DINNKKSVTD SIRDEYAFLQ KKYPSLANRN GTKYLARTLN RLLMHHIRDC LPELKTRINV LAAQYQSLLN SYGEPVDDKS ATLLQLITKF ATEYCNTIEG TAKYIETSEL CGGARICYIF HETFGRTLES VDPLGGLNTI DILTAIRNAT GPRPALFVPE VSFELLVKRQ IKRLEEPSLR CVELVHEEMQ RIIQHCSNYS TQELLRFPKL HDAIVEVVTC LLRKRLPVTN EMVHNLVAIE LAYINTKHPD FADACGLMNN NIEEQRRNRL ARELPSAVSR DKLIQDSRRE TKNVASGGGG VGDGVQEPTT GNWRGMLKTS KAEELLAEEK SKPIPIMPAS PQKGHAVNLL DVPVPVARKL SAREQRDCEV IERLIKSYFL IVRKNIQDSV PKAVMHFLVN HVKDTLQSEL VGQLYKSSLL DDLLTESEDM AQRRKEAADM LKALQGASQI IAEIRETHLW

Cross-Reactivity: Human

Characteristics: Antibody Reactive Against Recombinant Protein.

Immunogen: DNM1L (AAH24590.1, 1 a.a. ~ 710 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Isotype: IgG2b

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: In 1x PBS, pH 7.4

Handling Advice: Aliquot to avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

References for anti-Dynamin 1-Like antibody (ABIN564347)

Kim, McLean, Philip, Feldman: "Hyperinsulinemia induces insulin resistance in dorsal root ganglion neurons." in: Endocrinology, Vol. 152, Issue 10, pp. 3638-47, (2011) (PubMed).

Edwards, Quattrini, Lentz, Figueroa-Romero, Cerri, Backus, Hong, Feldman: "Diabetes regulates mitochondrial biogenesis and fission in mouse neurons." in: Diabetologia, Vol. 53, Issue 1, pp. 160-9, (2010) (PubMed).

Vincent, Edwards, McLean, Hong, Cerri, Lopez, Quattrini, Feldman: "Mitochondrial biogenesis and fission in axons in cell culture and animal models of diabetic neuropathy." in: Acta neuropathologica, Vol. 120, Issue 4, pp. 477-89, (2010) (PubMed).

Figueroa-Romero, Iñiguez-Lluhí, Stadler, Chang, Arnoult, Keller, Hong, Blackstone, Feldman: "SUMOylation of the mitochondrial fission protein Drp1 occurs at multiple nonconsensus sites within the B domain and is linked to its activity cycle." in: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 23, Issue 11, pp. 3917-27, (2009) (PubMed).

Target Details for Dynamin 1-Like

Target: Dynamin 1-Like (DNM1L)

Alternative Name: DNM1L

Background: Full Gene Name: dynamin 1-like
Synonyms: DLP1,DRP1,DVLP,DYMPLE,DYNIV-11,FLJ41912,HDYNIV,VPS1

Gene ID: 10059