INTS6 antibody (AA 135-167)

Catalog No. ABIN5647099

The Rabbit Polyclonal anti-INTS6 antibody is suitable to detect INTS6 in samples from Human. It has been validated for WB.

Quick Overview for INTS6 antibody (AA 135-167) (ABIN5647099)

Target: INTS6 (Integrator Complex Subunit 6 (INTS6))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This INTS6 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-INTS6 Antibody

Binding Specificity: AA 135-167

Purpose: INTS6 Antibody

Cross-Reactivity (Details): Expected species reactivity: Mouse

Purification: Antigen affinity

Immunogen: A portion of amino acids 135-167 from the human protein was used as the immunogen for the INTS6 antibody.

Isotype: Ig Fraction

Application Details

Application Notes: Titration of the INTS6 antibody may be required due to differences in protocols and substrate sensitivity.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the INTS6 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Target Details for INTS6

Target: INTS6 (Integrator Complex Subunit 6 (INTS6))

Alternative Name: INTS6

Background: Integrator complex subunit 6 is a component of the Integrator complex, a complex involved in the small nuclear RNAs (snRNA) U1 and U2 transcription and in their 3'-box-dependent processing. The Integrator complex is associated with the C-terminal domain (CTD) of RNA polymerase II largest subunit (POLR2A) and is recruited to the U1 and U2 snRNAs genes. May have a tumor suppressor role, an ectopic expression suppressing tumor cell growth.

Gene ID: 26512

UniProt: Q9UL03