Recombinant EGFR antibody (C-Term)

Catalog No. ABIN5647113

This Rabbit Monoclonal antibody specifically detects EGFR in WB and IHC. It exhibits reactivity toward Human.

Quick Overview for Recombinant EGFR antibody (C-Term) (ABIN5647113)

Target: EGFR (Epidermal Growth Factor Receptor (EGFR))

Antibody Type: Recombinant Antibody

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This EGFR antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Clone: RM294

Product Details anti-EGFR Antibody

Binding Specificity: C-Term

Purpose: Recombinant EGFR Antibody / C-Terminal

Characteristics: This antibody reacts to human EGF Receptor (c-ErbB-1, HER1). No cross reactivity with HER2, HER3, or HER4 is seen.

Purification: Protein A purified from animal origin-free supernatant

Immunogen: A peptide corresponding to the C-terminus of human EGF Receptor was used as the immunogen for the recombinant EGFR antibody.

Isotype: IgG

Application Details

Application Notes: The stated application concentrations are suggested starting points. Titration of the recombinant EGFR antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Antibody in PBS with 50 % glycerol, 1 % BSA and 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store the recombinant EGFR antibody at -20oC.

Target Details for EGFR

Target: EGFR (Epidermal Growth Factor Receptor (EGFR))

Alternative Name: EGFR

Background: This antibody reacts to human EGF Receptor (c-ErbB-1, HER1). No cross reactivity with HER2, HER3, or HER4 is seen.

UniProt: P00533

Pathways: NF-kappaB Signaling, RTK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Stem Cell Maintenance, Hepatitis C, Positive Regulation of Response to DNA Damage Stimulus, Interaction of EGFR with phospholipase C-gamma, Thromboxane A2 Receptor Signaling, EGFR Downregulation, S100 Proteins