LBP antibody

Catalog No. ABIN5647188

This Rabbit Polyclonal antibody specifically detects LBP in WB and ELISA (Capture). It exhibits reactivity toward Mouse.

Quick Overview for LBP antibody (ABIN5647188)

Target: LBP (Lipopolysaccharide Binding Protein (LBP))

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LBP antibody is un-conjugated

Application: Western Blotting (WB), ELISA (Capture)

Product Details anti-LBP Antibody

Purification: Antigen affinity purified

Immunogen: A recombinant mouse protein corresponding to amino acids V26-R257 was used as the immunogen for the LBP antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the LBP antibody should be determined by the researcher.\. Western Blot: 0.5-1 μg/mL,ELISA (Capture, recombinant mouse protein): 0.1-0.5 μg/mL (BSA-free format available)

Restrictions: For Research Use only

Handling

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: -20 °C

Storage Comment: After reconstitution, the LBP antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Target Details for LBP

Target: LBP (Lipopolysaccharide Binding Protein (LBP))

Alternative Name: LBP / Lipopolysaccharide Binding Protein

Background: Lipopolysaccharide binding protein is a protein that in humans is encoded by the LBP gene. The protein encoded by this gene is involved in the acute-phase immunologic response to gram-negative bacterial infections. Gram-negative bacteria contain a glycolipid, lipopolysaccharide (LPS), on their outer cell wall. Together with bactericidal permeability-increasing protein (BPI), the encoded protein binds LPS and interacts with the CD14 receptor, probably playing a role in regulating LPS-dependent monocyte responses. Studies in mice suggest that the encoded protein is necessary for the rapid acute-phase response to LPS but not for the clearance of LPS from circulation. This protein is part of a family of structurally and functionally related proteins, including BPI, plasma cholesteryl ester transfer protein (CETP), and phospholipid transfer protein (PLTP).

UniProt: Q61805

Pathways: TLR Signaling, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Immune Effector Process, Toll-Like Receptors Cascades, Monocarboxylic Acid Catabolic Process