Titin antibody (AA 7169-7203)

Catalog No. ABIN5647294

Product Details anti-Titin Antibody

Target: Titin (TTN)

Binding Specificity: AA 7169-7203

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Titin antibody is un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Cross-Reactivity (Details): Expected species reactivity: Mouse

Purification: Antigen affinity purified

Immunogen: A portion of amino acids 7169-7203 from the human protein was used as the immunogen for the Titin antibody.

Isotype: Ig Fraction

Application Details

Application Notes: IHC (FFPE): 1:25

Restrictions: For Research Use only

Handling

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the Titin antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Target Details for Titin

Target: Titin (TTN)

Alternative Name: Titin / TTN (TTN Products)

Synonyms: CMD1G antibody, CMH9 antibody, CMPD4 antibody, EOMFC antibody, HMERF antibody, LGMD2J antibody, MYLK5 antibody, TMD antibody, 1100001C23Rik antibody, 2310036G12Rik antibody, 2310057K23Rik antibody, 2310074I15Rik antibody, AF006999 antibody, AV006427 antibody, D330041I19Rik antibody, D830007G01Rik antibody, L56 antibody, mdm antibody, shru antibody, UNC-22 antibody, titin antibody, TTN antibody, Ttn antibody, titin antibody, TTNLOC100620261 antibody

Background: Titin is a key component in the assembly and functioning of vertebrate striated muscles. By providing connections at the level of individual microfilaments, it contributes to the fine balance of forces between the two halves of the sarcomere. The size and extensibility of the cross-links are the main determinants of sarcomere extensibility properties of muscle. In non-muscle cells, seems to play a role in chromosome condensation and chromosome segregation during mitosis. Might link the lamina network to chromatin or nuclear actin, or both during interphase.

Gene ID: 7273

UniProt: Q8WZ42