FBXO32
Reactivity: Human
WB
Host: Rabbit
Polyclonal
unconjugated
Application Notes
Western blot: 1:1000-2000
Restrictions
For Research Use only
Buffer
In 1X PBS, pH 7.4, with 0.09 % sodium azide
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
-20 °C
Storage Comment
Aliquot the Atrogin 1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Target
FBXO32
(F-Box Protein 32 (FBXO32))
Alternative Name
Atrogin 1 / FBXO32
Background
F-box only protein 32 / Atrogin 1 is a substrate recognition component of a SCF (SKP1-CUL1-F- box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Probably recognizes and binds to phosphorylated target proteins during skeletal muscle atrophy. Recognizes TERF1.