Recombinant CDKN1B antibody (C-Term)

Catalog No. ABIN5647435

The Rabbit Monoclonal anti-CDKN1B antibody has been validated for WB and IHC. It is suitable to detect CDKN1B in samples from Human.

Quick Overview for Recombinant CDKN1B antibody (C-Term) (ABIN5647435)

Target: CDKN1B (Cyclin-Dependent Kinase Inhibitor 1B (p27, Kip1) (CDKN1B))

Antibody Type: Recombinant Antibody

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This CDKN1B antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Clone: RM302

Product Details anti-CDKN1B Antibody

Binding Specificity: C-Term

Cross-Reactivity (Details): Expected species reactivity: Mouse

Characteristics: This antibody reacts to human p27Kip1 (Cyclin-dependent kinase inhibitor 1B). It may also react to mouse p27Kip1, as predicted by immunogen homology.

Purification: Purified

Immunogen: A peptide corresponding to the C-terminus of human p27Kip1 was used as the immunogen for the recombinant p27 antibody.

Isotype: IgG

Application Details

Application Notes: The stated application concentrations are suggested starting points. Titration of the recombinant p27 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Immunohistochemistry (FFPE): 1:100-1:200,Western Blot: 1:500-1:1000

Restrictions: For Research Use only

Handling

Buffer: Antibody in PBS with 50 % Glycerol, 1 % BSA and 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store the recombinant p27 antibody at -20°C.

Target Details for CDKN1B

Target: CDKN1B (Cyclin-Dependent Kinase Inhibitor 1B (p27, Kip1) (CDKN1B))

Alternative Name: p27 / p27Kip1

Background: This antibody reacts to human p27Kip1 (Cyclin-dependent kinase inhibitor 1B). It may also react to mouse p27Kip1, as predicted by immunogen homology.

UniProt: P46527

Pathways: Cell Division Cycle, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Positive Regulation of Peptide Hormone Secretion, Negative Regulation of Hormone Secretion, Sensory Perception of Sound, Mitotic G1-G1/S Phases, DNA Replication, Positive Regulation of Endopeptidase Activity, Synthesis of DNA, Autophagy