Acetylcholinesterase antibody (AA 147-175)

Catalog No. ABIN7479774

The Rabbit Polyclonal anti-Acetylcholinesterase antibody is suitable to detect Acetylcholinesterase in samples from Human. It has been validated for WB, ELISA, IF, IHC (p) and FACS.

Quick Overview for Acetylcholinesterase antibody (AA 147-175) (ABIN7479774)

Target: Acetylcholinesterase (AChE)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Acetylcholinesterase antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)

Product Details anti-Acetylcholinesterase Antibody

Binding Specificity: AA 147-175

Purpose: Acetylcholinesterase Antibody / ACHE

Cross-Reactivity (Details): Expected species reactivity: Guinea pig

Purification: Purified

Immunogen: A portion of amino acids 147-175 from the human protein was used as the immunogen for this Acetylcholinesterase antibody.

Isotype: Ig Fraction

Application Details

Application Notes: Titration of the Acetylcholinesterase antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the Acetylcholinesterase antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Target Details for Acetylcholinesterase

Target: Acetylcholinesterase (AChE)

Alternative Name: Acetylcholinesterase

Background: Acetylcholinesterase hydrolyzes the neurotransmitter, acetylcholine at neuromuscular junctions and brain cholinergic synapses, and thus terminates signal transmission. The Protein is also found on the red blood cell membranes, where it constitutes the Yt blood group antigen. Acetylcholinesterase exists in multiple molecular forms which possess similar catalytic properties, but differ in their oligomeric assembly and mode of cell attachment to the cell surface. The major form of acetylcholinesterase found in brain, muscle and other tissues is the hydrophilic species, which forms disulfide-linked oligomers with collagenous, or lipid-containing structural subunits.

UniProt: P22303

Pathways: Skeletal Muscle Fiber Development