FERMT3 antibody (AA 117-151)

Catalog No. ABIN7479935

The Rabbit Polyclonal anti-FERMT3 antibody (ABIN7479935) specifically detects FERMT3 in WB. The antibody is reactive with Mouse samples.

Quick Overview for FERMT3 antibody (AA 117-151) (ABIN7479935)

Target: FERMT3 (Fermitin Family Member 3 (FERMT3))

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FERMT3 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-FERMT3 Antibody

Binding Specificity: AA 117-151

Purpose: Kindlin-3 Antibody / FERMT3

Cross-Reactivity (Details): Expected species reactivity: Human,Bovine

Purification: Antigen affinity

Immunogen: A portion of amino acids 117-151 from the mouse protein was used as the immunogen for the Kindlin-3 antibody.

Isotype: Ig Fraction

Application Details

Application Notes: Titration of the Kindlin-3 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the Kindlin-3 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Target Details for FERMT3

Target: FERMT3 (Fermitin Family Member 3 (FERMT3))

Alternative Name: Kindlin-3

Background: Fermitin family homolog 3, also called Kindlin-3, plays a central role in cell adhesion in hematopoietic cells. Acts by activating the integrin beta-1-3 (ITGB1, ITGB2 and ITGB3). Required for integrin-mediated platelet adhesion and leukocyte adhesion to endothelial cells. Required for activation of integrin beta-2 (ITGB2) in polymorphonuclear granulocytes (PMNs) (By similarity).

UniProt: Q86UX7