FERMT3 antibody (AA 117-151)

Catalog No. ABIN5647835

Product Details anti-FERMT3 Antibody

Target: FERMT3 (Fermitin Family Member 3 (FERMT3))

Binding Specificity: AA 117-151

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FERMT3 antibody is un-conjugated

Application: Western Blotting (WB)

Cross-Reactivity (Details): Expected species reactivity: Human,Bovine

Purification: Antigen affinity purified

Immunogen: A portion of amino acids 117-151 from the mouse protein was used as the immunogen for the Kindlin-3 antibody.

Isotype: Ig Fraction

Application Details

Application Notes: Western blot: 1:1000-2000

Restrictions: For Research Use only

Handling

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the Kindlin-3 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Target Details for FERMT3

Target: FERMT3 (Fermitin Family Member 3 (FERMT3))

Alternative Name: Kindlin-3 / URP2 / FERMT3 (FERMT3 Products)

Synonyms: C79673 antibody, Kindlin3 antibody, RGD1310168 antibody, MGC69069 antibody, MGC88900 antibody, KIND3 antibody, MIG-2 antibody, MIG2B antibody, UNC112C antibody, URP2 antibody, URP2SF antibody, zgc:64101 antibody, fermitin family member 3 antibody, fermitin family member 3 L homeolog antibody, fermitin family member 3b antibody, Fermt3 antibody, fermt3.L antibody, fermt3 antibody, FERMT3 antibody, fermt3b antibody

Background: Fermitin family homolog 3, also called Kindlin-3, plays a central role in cell adhesion in hematopoietic cells. Acts by activating the integrin beta-1-3 (ITGB1, ITGB2 and ITGB3). Required for integrin-mediated platelet adhesion and leukocyte adhesion to endothelial cells. Required for activation of integrin beta-2 (ITGB2) in polymorphonuclear granulocytes (PMNs) (By similarity).

Gene ID: 83706

UniProt: Q86UX7