PHGDH antibody (AA 1-533)

Catalog No. ABIN565240

This Mouse Monoclonal antibody specifically detects PHGDH in WB, ELISA, IHC (p), IF and IP. It exhibits reactivity toward Humanand has been mentioned in 1 publication.

Quick Overview for PHGDH antibody (AA 1-533) (ABIN565240)

Target: PHGDH (phosphoglycerate Dehydrogenase (PHGDH))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This PHGDH antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF), Immunoprecipitation (IP)

Clone: 4A3-1D6

Product Details anti-PHGDH Antibody

Binding Specificity: AA 1-533

Purpose: Mouse monoclonal antibody raised against a full length recombinant PHGDH.

Sequence: MAFANLRKVL ISDSLDPCCR KILQDGGLQV VEKQNLSKEE LIAELQDCEG LIVRSATKVT ADVINAAEKL QVVGRAGTGV DNVDLEAATR KGILVMNTPN GNSLSAAELT CGMIMCLARQ IPQATASMKD GKWERKKFMG TELNGKTLGI LGLGRIGREV ATRMQSFGMK TIGYDPIISP EVSASFGVQQ LPLEEIWPLC DFITVHTPLL PSTTGLLNDN TFAQCKKGVR VVNCARGGIV DEGALLRALQ SGQCAGAALD VFTEEPPRDR ALVDHENVIS CPHLGASTKE AQSRCGEEIA VQFVDMVKGK SLTGVVNAQA LTSAFSPHTK PWIGLAEALG TLMRAWAGSP KGTIQVITQG TSLKNAGNCL SPAVIVGLLK EASKQADVNL VNAKLLVKEA GLNVTTSHSP AAPGEQGFGE CLLAVALAGA PYQAVGLVQG TTPVLQGLNG AVFRPEVPLR RDLPLLLFRT QTSDPAMLPT MIGLLAEAGV RLLSYQTSLV SDGETWHVMG ISSLLPSLEA WKQHVTEAFQ FHF

Cross-Reactivity: Human

Characteristics: Antibody Reactive Against Recombinant Protein.

Immunogen: PHGDH (AAH11262.1, 1 a.a. ~ 533 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Isotype: IgG1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: In 1x PBS, pH 7.4

Handling Advice: Aliquot to avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

References for anti-PHGDH antibody (ABIN565240)

Pollari, Käkönen, Edgren, Wolf, Kohonen, Sara, Guise, Nees, Kallioniemi: "Enhanced serine production by bone metastatic breast cancer cells stimulates osteoclastogenesis." in: Breast cancer research and treatment, Vol. 125, Issue 2, pp. 421-30, (2010) (PubMed).

Target Details for PHGDH

Target: PHGDH (phosphoglycerate Dehydrogenase (PHGDH))

Alternative Name: PHGDH

Background: Full Gene Name: phosphoglycerate dehydrogenase
Synonyms: 3-PGDH,3PGDH,MGC3017,PDG,PGAD,PGD,PGDH,SERA

Gene ID: 26227

Pathways: Metabolism of Steroid Hormones and Vitamin D, Warburg Effect