GDAP1 antibody (AA 158-257)

Catalog No. ABIN565729

This Mouse Polyclonal antibody specifically detects GDAP1 in WB and ELISA. It exhibits reactivity toward Human. It has been mentioned in 3+ publications

Quick Overview for GDAP1 antibody (AA 158-257) (ABIN565729)

Target: GDAP1 (Ganglioside-Induced Differentiation-Associated Protein 1 (GDAP1))

Reactivity: Human

Host: Mouse

Clonality: Polyclonal

Conjugate: This GDAP1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-GDAP1 Antibody

Binding Specificity: AA 158-257

Purpose: Mouse polyclonal antibody raised against a partial recombinant GDAP1.

Sequence: TRIRSQIGNT ESELKKLAEE NPDLQEAYIA KQKRLKSKLL DHDNVKYLKK ILDELEKVLD QVETELQRRN EETPEEGQQP WLCGESFTLA DVSLAVTLHR

Cross-Reactivity: Human

Characteristics: Antibody Reactive Against Recombinant Protein.

Immunogen: GDAP1 (NP_061845, 158 a.a. ~ 257 a.a) partial recombinant protein with GST tag.

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: 50 % glycerol

Handling Advice: Aliquot to avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

References for anti-GDAP1 antibody (ABIN565729)

Pla-Martín, Rueda, Estela, Sánchez-Piris, González-Sánchez, Traba, de la Fuente, Scorrano, Renau-Piqueras, Alvarez, Satrústegui, Palau: "Silencing of the Charcot-Marie-Tooth disease-associated gene GDAP1 induces abnormal mitochondrial distribution and affects Ca2+ homeostasis by reducing store-operated Ca2+ entry." in: Neurobiology of disease, Vol. 55, pp. 140-51, (2013) (PubMed).

Estela, Pla-Martín, Sánchez-Piris, Sesaki, Palau: "Charcot-Marie-Tooth-related gene GDAP1 complements cell cycle delay at G2/M phase in Saccharomyces cerevisiae fis1 gene-defective cells." in: The Journal of biological chemistry, Vol. 286, Issue 42, pp. 36777-86, (2011) (PubMed).

Cassereau, Chevrollier, Gueguen, Malinge, Letournel, Nicolas, Richard, Ferre, Verny, Dubas, Procaccio, Amati-Bonneau, Bonneau, Reynier: "Mitochondrial complex I deficiency in GDAP1-related autosomal dominant Charcot-Marie-Tooth disease (CMT2K)." in: Neurogenetics, Vol. 10, Issue 2, pp. 145-50, (2009) (PubMed).

Target Details for GDAP1

Target: GDAP1 (Ganglioside-Induced Differentiation-Associated Protein 1 (GDAP1))

Alternative Name: GDAP1

Background: Full Gene Name: ganglioside-induced differentiation-associated protein 1
Synonyms:

Gene ID: 54332

NCBI Accession: NM_018972