NDE1 antibody (AA 1-335)

Catalog No. ABIN565777

This Mouse Monoclonal antibody specifically detects NDE1 in WB, ELISA and IF. It exhibits reactivity toward Human and has been mentioned in 2+ publications.

Quick Overview for NDE1 antibody (AA 1-335) (ABIN565777)

Target: NDE1

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This NDE1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF)

Clone: 2G11-1C11

Product Details anti-NDE1 Antibody

Binding Specificity: AA 1-335

Purpose: Mouse monoclonal antibody raised against a full length recombinant NDE1.

Sequence: MEDSGKTFSS EEEEANYWKD LAMTYKQRAE NTQEELREFQ EGSREYEAEL ETQLQQIETR NRDLLSENNR LRMELETIKE KFEVQHSEGY RQISALEDDL AQTKAIKDQL QKYIRELEQA NDDLERAKRA TIMSLEDFEQ RLNQAIERNA FLESELDEKE NLLESVQRLK DEARDLRQEL AVQQKQEKPR TPMPSSVEAE RTDTAVQATG SVPSTPIAHR GPSSSLNTPG SFRRGLDDST GGTPLTPAAR ISALNIVGDL LRKVGALESK LASCRNLVYD QSPNRTGGPA SGRSSKNRDG GERRPSSTSV PLGDKGLDTS CRWLSKSTTR SSSSC

Cross-Reactivity: Human

Characteristics: Antibody Reactive Against Recombinant Protein.

Immunogen: NDE1 (AAH01421, 1 a.a. ~ 335 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Isotype: IgG1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: In 1x PBS, pH 7.4

Handling Advice: Aliquot to avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

References for anti-NDE1 antibody (ABIN565777)

Doobin, Kemal, Dantas, Vallee: "Severe NDE1-mediated microcephaly results from neural progenitor cell cycle arrests at multiple specific stages." in: Nature communications, Vol. 7, pp. 12551, (2016) (PubMed).

Bradshaw, Christie, Soares, Carlyle, Porteous, Millar: "NDE1 and NDEL1: multimerisation, alternate splicing and DISC1 interaction." in: Neuroscience letters, Vol. 449, Issue 3, pp. 228-33, (2008) (PubMed).

Target Details for NDE1

Target: NDE1

Alternative Name: NDE1

Background: Full Gene Name: nudE nuclear distribution gene E homolog 1 (A. nidulans)
Synonyms: FLJ20101,HOM-TES-87,NUDE,NUDE1

Gene ID: 54820