POLE4 antibody (AA 31-117)

Catalog No. ABIN566035

This Mouse Polyclonal antibody specifically detects POLE4 in ELISA and WB. It exhibits reactivity toward Humanand has been mentioned in 1 publication.

Quick Overview for POLE4 antibody (AA 31-117) (ABIN566035)

Target: POLE4 (Polymerase (DNA-Directed), epsilon 4 (p12 Subunit) (POLE4))

Reactivity: Human

Host: Mouse

Clonality: Polyclonal

Conjugate: This POLE4 antibody is un-conjugated

Application: ELISA, Western Blotting (WB)

Product Details anti-POLE4 Antibody

Binding Specificity: AA 31-117

Purpose: Mouse polyclonal antibody raised against a partial recombinant POLE4.

Sequence: TSVPGARLSR LPLARVKALV KADPDVTLAG QEAIFILARA AELFVETIAK DAYCCAQQGK RKTLQRRDLD NAIEAVDEFA FLEGTLD

Cross-Reactivity: Human

Characteristics: Antibody Reactive Against Recombinant Protein.

Immunogen: POLE4 (NP_063949, 31 a.a. ~ 117 a.a) partial recombinant protein with GST tag.

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: 50 % glycerol

Handling Advice: Aliquot to avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

References for anti-POLE4 antibody (ABIN566035)

Pachlopnik Schmid, Lemoine, Nehme, Cormier-Daire, Revy, Debeurme, Debré, Nitschke, Bole-Feysot, Legeai-Mallet, Lim, de Villartay, Picard, Durandy, Fischer, de Saint Basile: "Polymerase ?1 mutation in a human syndrome with facial dysmorphism, immunodeficiency, livedo, and short stature ("FILS syndrome")." in: The Journal of experimental medicine, Vol. 209, Issue 13, pp. 2323-30, (2012) (PubMed).

Target Details for POLE4

Target: POLE4 (Polymerase (DNA-Directed), epsilon 4 (p12 Subunit) (POLE4))

Alternative Name: POLE4

Background: Full Gene Name: polymerase (DNA-directed), epsilon 4 (p12 subunit)
Synonyms: p12

Gene ID: 56655

NCBI Accession: NM_019896

Pathways: DNA Damage Repair