LBP antibody

Catalog No. ABIN5663310

This Mouse Monoclonal antibody specifically detects LBP in ELISA. It exhibits reactivity toward Human.

Quick Overview for LBP antibody (ABIN5663310)

Target: LBP (Lipopolysaccharide Binding Protein (LBP))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This LBP antibody is un-conjugated

Application: ELISA

Clone: BiG48

Product Details anti-LBP Antibody

Specificity: Human LBP (Lipopolysaccaride binding protein). The antibody don't block LPS binding to membrane bound CD14.

Cross-Reactivity: Cow (Bovine), Dog (Canine), Horse (Equine), Rabbit

Cross-Reactivity (Details): pork, rabbit, dog, horse, bovine LBP

Purification: Protein A affinity column

Immunogen: native human LBP

Isotype: IgG1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Reconstitute with bidistilled water

Concentration: 1 mg/mL

Buffer: PBS, pH 7.14

Preservative: Without preservative

Storage: -20 °C,-80 °C

Target Details for LBP

Target: LBP (Lipopolysaccharide Binding Protein (LBP))

Alternative Name: LBP

Background: Background: Natural Lipopolysccaride Binding Protein (LBP) is a 58KD glycoprotein produced in liver. It binds at lipid A of LPS with high affinity (10-9M) and reduced the cellular LPS effects at CD14+ cells (IL1ß, IL6, TNFα). It acts as opsonin for GRAM negative cells, LPS, neutrophiles and granulocytes.

Molecular Weight: ~58kDa

Gene ID: 3929

NCBI Accession: NP_004130

UniProt: P18428

Pathways: TLR Signaling, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Immune Effector Process, Toll-Like Receptors Cascades, Monocarboxylic Acid Catabolic Process