LBP antibody (HRP)

Catalog No. ABIN5663313

This Mouse Monoclonal antibody specifically detects LBP in ELISA. It exhibits reactivity toward Mouse.

Quick Overview for LBP antibody (HRP) (ABIN5663313)

Target: LBP (Lipopolysaccharide Binding Protein (LBP))

Reactivity: Mouse

Host: Mouse

Clonality: Monoclonal

Conjugate: This LBP antibody is conjugated to HRP

Application: ELISA

Clone: BiG33

Product Details anti-LBP Antibody (HRP)

Specificity: Mouse LBP

Cross-Reactivity: Human, Rat (Rattus)

Cross-Reactivity (Details): rat LBP, human LBP

Purification: Protein G affinity column

Immunogen: native mouse LBP

Isotype: IgG1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS, pH 7.19

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Target Details for LBP

Target: LBP (Lipopolysaccharide Binding Protein (LBP))

Alternative Name: LBP

Background: Background: Natural Lipopolysccaride Binding Protein (LBP) is a 58KD glycoprotein produced in liver. It binds at lipid A of LPS with high affinity (10-9M) and reduced the cellular LPS effects at CD14+ cells (IL1ß, IL6, TNFα). It acts as opsonin for GRAM negative cells, LPS, neutrophiles and granulocytes.

Molecular Weight: ~58kDa

Gene ID: 16803

UniProt: Q61805

Pathways: TLR Signaling, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Immune Effector Process, Toll-Like Receptors Cascades, Monocarboxylic Acid Catabolic Process