CD14 antibody

Catalog No. ABIN5663314

The Rabbit Polyclonal anti-CD14 antibody is suitable to detect CD14 in samples from Human.

Quick Overview for CD14 antibody (ABIN5663314)

Target: CD14

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CD14 antibody is un-conjugated

Application: Please inquire

Product Details anti-CD14 Antibody

Specificity: Human CD14

Purification: unpurified antiserum

Immunogen: recombinant human CD14

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Reconstitute with bidistilled water

Buffer: PBS, pH 7.21

Preservative: Without preservative

Storage: -20 °C,-80 °C

Target Details for CD14

Target: CD14

Alternative Name: CD14

Background: Background: huCD14 antiserum represents an excellent marker for CD14. The CD14 glycoprotein, gp 55, is present on most monocytic and macrophages like cell types: monocytes, macrophages, weekly at surface of neutrophiles like Kupffer cells, pleural phagocytic cells and dendritic reticular cells. CD14 is also observed on granulocytes and activated or transformed B-cells. Furthermore CD14 is present in a soluble form in human serum, urine and other body fluids. The CD14 Molecule has been reported to be a receptor for endotoxin. CD14 is anchored to cells by linkage to glycosylphosphatidylinositol (GPI) and functions as a high affinity receptor for LPS-LBP (lipopolysaccharide binding protein)-complexes.

Molecular Weight: ~50kDa

Gene ID: 929

NCBI Accession: NP_000582

UniProt: P08571

Pathways: TLR Signaling, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades