E2F8 antibody (AA 1-431)

Catalog No. ABIN566378

There are 4+ publications for this product available. The Mouse Monoclonal anti-E2F8 antibody is suitable to detect E2F8 in samples from Human. It has been validated for WB and ELISA.

Quick Overview for E2F8 antibody (AA 1-431) (ABIN566378)

Target: E2F8 (E2F Transcription Factor 8 (E2F8))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This E2F8 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Clone: 3E9-2F5

Product Details anti-E2F8 Antibody

Binding Specificity: AA 1-431

Purpose: Mouse monoclonal antibody raised against a full length recombinant FLJ23311.

Sequence: MAQLAAICKM QLEEQSSESR QKVKVQLARS GPCKPVAPLD PPVNAEMELT APSLIQPLGM VPLIPSPLSS AVPLILPQAP SGPSYAIYLQ PTQAHQSVTP PQGLSPTVCT THSSKATGSK DSTDATTEKA ANDTSKASAS TRPGSLLPAP ERQGAKSRTR EPAGERGSKR ASMLEDSGSK KKFKEDLKGL ENVSATLFPS GYLIPLTQCS SLGAESILSG KENSSALSPN HRIYSSPIAG VIPVTSSELT AVNFPSFHVT PLKLMVSPTS VAAVPVGNSP ALASSHPVPI QNPSSAIVNF TLQHLGLISP NVQLSASPGS GIVPVSPRIE SVNVAPENAG TQQGRATNYD SPVPGQSQPN GQSVAVTGAQ QPVPVTPKGS QLVAESFFRT PGGPTKPTSS SCMDFEGANK TSLGTLFVPQ RKLEVSTEDV H

Cross-Reactivity: Human

Characteristics: Antibody Reactive Against Recombinant Protein.

Immunogen: E2F8 (AAH28244, 1 a.a. ~ 431 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Isotype: IgG1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: In 1x PBS, pH 7.4

Handling Advice: Aliquot to avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

References for anti-E2F8 antibody (ABIN566378)

de Bruin, A Cornelissen, Kirchmaier, Mokry, Iich, Nirmala, Liang, D Végh, Scholman, Groot Koerkamp, Holstege, Cuppen, Schulte-Merker, Bakker: "Genome-wide analysis reveals NRP1 as a direct HIF1α-E2F7 target in the regulation of motorneuron guidance in vivo." in: Nucleic acids research, Vol. 44, Issue 8, pp. 3549-66, (2016) (PubMed).

Deng, Wang, Zong, Zheng, Wen, Wang, Teng, Zhang, Huang, Han: "E2F8 contributes to human hepatocellular carcinoma via regulating cell proliferation." in: Cancer research, Vol. 70, Issue 2, pp. 782-91, (2010) (PubMed).

Li, Ran, Li, Gordon, Comstock, Siddiqui, Cleghorn, Chen, Kornacker, Liu, Pandit, Khanizadeh, Weinstein, Leone, de Bruin: "Synergistic function of E2F7 and E2F8 is essential for cell survival and embryonic development." in: Developmental cell, Vol. 14, Issue 1, pp. 62-75, (2008) (PubMed).

Zalmas, Zhao, Graham, Fisher, Reilly, Coutts, La Thangue: "DNA-damage response control of E2F7 and E2F8." in: EMBO reports, Vol. 9, Issue 3, pp. 252-9, (2008) (PubMed).

Target Details for E2F8

Target: E2F8 (E2F Transcription Factor 8 (E2F8))

Alternative Name: E2F8

Background: Full Gene Name: E2F transcription factor 8
Synonyms: FLJ23311

Gene ID: 79733