CYGB antibody (AA 1-190)

Catalog No. ABIN566715

Cited in 5+ publications. The Mouse Monoclonal anti-CYGB antibody (Clone 1A1) (ABIN566715) specifically detects CYGB in WB, ELISA, IF and IHC (p). The antibody is reactive with Human samples.

Quick Overview for CYGB antibody (AA 1-190) (ABIN566715)

Target: CYGB (Cytoglobin (CYGB))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CYGB antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: 1A1

Product Details anti-CYGB Antibody

Binding Specificity: AA 1-190

Purpose: Mouse monoclonal antibody raised against a full length recombinant CYGB.

Sequence: MEKVPGEMEI ERRERSEELS EAERKAVQAM WARLYASCED VGVAILVRFF VNFPSAKQYF SQFKHMEDPL EMERSPQLRK HACRVMGALN TVVENLHDPD KVSSVLALVG KAHALKHKVE PVYFKILSGV ILEVVAEEFA SDFPPETQRA WAKLRGLIYS HVTAAYKEVG WVQQVPNATT PPATLPSSGP

Cross-Reactivity: Human

Characteristics: Antibody Reactive Against Recombinant Protein.

Immunogen: CYGB (AAH29798, 1 a.a. ~ 190 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Isotype: IgG1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: In 1x PBS, pH 7.4

Handling Advice: Aliquot to avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

References for anti-CYGB antibody (ABIN566715)

John, Chand, Chakraborty, Jaiswal, Nag: "DNA damage induced activation of Cygb stabilizes p53 and mediates G1 arrest." in: DNA repair, Vol. 24, pp. 107-12, (2014) (PubMed).

Oleksiewicz, Liloglou, Tasopoulou, Daskoulidou, Bryan, Gosney, Field, Xinarianos: "Cytoglobin has bimodal: tumour suppressor and oncogene functions in lung cancer cell lines." in: Human molecular genetics, Vol. 22, Issue 16, pp. 3207-17, (2013) (PubMed).

Basu, Drame, Muñoz, Gijsbers, Debyser, De Leon, Casiano: "Pathway specific gene expression profiling reveals oxidative stress genes potentially regulated by transcription co-activator LEDGF/p75 in prostate cancer cells." in: The Prostate, Vol. 72, Issue 6, pp. 597-611, (2012) (PubMed).

Li, Lee, Pouranfar, Brittian, Clair, Row, Wang, Gozal: "Hypoxia differentially regulates the expression of neuroglobin and cytoglobin in rat brain." in: Brain research, Vol. 1096, Issue 1, pp. 173-9, (2006) (PubMed).

Powers: "p53-mediated apoptosis, neuroglobin overexpression, and globin deposits in a patient with hereditary ferritinopathy." in: Journal of neuropathology and experimental neurology, Vol. 65, Issue 7, pp. 716-21, (2006) (PubMed).

Target Details for CYGB

Target: CYGB (Cytoglobin (CYGB))

Alternative Name: CYGB

Background: Full Gene Name: cytoglobin
Synonyms: HGB,STAP

Gene ID: 114757