CYGB antibody (AA 1-60)

Catalog No. ABIN7228140

This Rabbit Polyclonal antibody specifically detects CYGB in ELISA, IHC and IF. It exhibits reactivity toward Human, Rat and Mouse.

Quick Overview for CYGB antibody (AA 1-60) (ABIN7228140)

Target: CYGB (Cytoglobin (CYGB))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CYGB antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-CYGB Antibody

Binding Specificity: AA 1-60

Purpose: Rabbit Anti-Cytoglobin Polyclonal Antibody

Specificity: The antibody detects endogenous levels of Cytoglobin

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human Cytoglobin protein at AA range: 1-60

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC 1:50-200,ELISA 1:10000-20000,IF 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for CYGB

Target: CYGB (Cytoglobin (CYGB))

Alternative Name: Cytoglobin

Background: Cytoglobin, Histoglobin, HGb, Stellate cell activation-associated proteinCYGB encodes a globin protein found in vertebrate cells. The encoded protein is described as a hexacoordinate hemoglobin which binds ligand differently from the pentacoordinate hemoglobins involved in oxygen transport, and may be involved in protection during oxidative stress. CYGB is located on chromosome 17 in the same region as a retinal gene which is mutated in progressive rod-cone degeneration, but in the opposite orientation. CYGB (Cytoglobin) is a Protein Coding gene. Diseases associated with CYGB include Ancylostomiasis. Among its related pathways are eNOS activation and regulation and Metabolism.

Gene ID: 114757

UniProt: Q8WWM9