TWIST2 antibody (AA 1-160)

Catalog No. ABIN566756

Product Details anti-TWIST2 Antibody

Target: TWIST2 (Twist Homolog 2 (TWIST2))

Binding Specificity: AA 1-160

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This TWIST2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purpose: Mouse monoclonal antibody raised against a full length recombinant TWIST2.

Sequence: MEEGSSSPVS PVDSLGTSEE ELERQPKRFG RKRRYSKKSS EDGSPTPGKR GKKGSPSAQS FEELQSQRIL ANVRERQRTQ SLNEAFAALR KIIPTLPSDK LSKIQTLKLA ARYIDFLYQV LQSDEMDNKM TSCSYVAHER LSYAFSVWRM EGSWSMSASH

Cross-Reactivity: Human

Characteristics: Antibody Reactive Against Recombinant Protein.

Immunogen: TWIST2 (AAH33168, 1 a.a. ~ 160 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Clone: 3C8

Isotype: IgG1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: In 1x PBS, pH 7.4

Handling Advice: Aliquot to avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

References for anti-TWIST2 antibody (ABIN566756)

Oh, Oh, Lee, Oh, Jeon, Choi, Hwang, Lee, Lee, Seong: "Expression of Twist2 is controlled by T-cell receptor signaling and determines the survival and death of thymocytes." in: Cell death and differentiation, Vol. 23, Issue 11, pp. 1804-1814, (2016) (PubMed).

Yu, Jin, Liu, Dong, Yu, Duan, Li, Dong, Cong, Yang: "Twist2 is a valuable prognostic biomarker for colorectal cancer." in: World journal of gastroenterology : WJG, Vol. 19, Issue 15, pp. 2404-11, (2013) (PubMed).

Rodrigues, Lavorato-Rocha, de M Maia, Stiepcich, de Carvalho, Baiocchi, Soares, Rocha: "Epithelial-mesenchymal transition-like events in vulvar cancer and its relation with HPV." in: British journal of cancer, Vol. 109, Issue 1, pp. 184-94, (2013) (PubMed).

Mao, Zhang, Xu, Ding, Zong, Liu: "Significance of heterogeneous Twist2 expression in human breast cancers." in: PLoS ONE, Vol. 7, Issue 10, pp. e48178, (2012) (PubMed).

Fang, Cai, Liu, Wang, Wu, Zhang, Yang, Yuan, Ouyang: "Twist2 contributes to breast cancer progression by promoting an epithelial-mesenchymal transition and cancer stem-like cell self-renewal." in: Oncogene, Vol. 30, Issue 47, pp. 4707-20, (2011) (PubMed).

Plasilova, Chattopadhyay, Ghosh, Wenzel, Demougin, Noppen, Schaub, Szinnai, Terracciano, Heinimann: "Discordant gene expression signatures and related phenotypic differences in lamin A- and A/C-related Hutchinson-Gilford progeria syndrome (HGPS)." in: PLoS ONE, Vol. 6, Issue 6, pp. e21433, (2011) (PubMed).

Doreau, Belot, Bastid, Riche, Trescol-Biemont, Ranchin, Fabien, Cochat, Pouteil-Noble, Trolliet, Durieu, Tebib, Kassai, Ansieau, Puisieux, Eliaou, Bonnefoy-Bérard: "Interleukin 17 acts in synergy with B cell-activating factor to influence B cell biology and the pathophysiology of systemic lupus erythematosus." in: Nature immunology, Vol. 10, Issue 7, pp. 778-85, (2009) (PubMed).

Murakami, Ohkuma, Nakamura: "Molecular mechanism of transforming growth factor-beta-mediated inhibition of growth arrest and differentiation in a myoblast cell line." in: Development, growth & differentiation, Vol. 50, Issue 2, pp. 121-30, (2008) (PubMed).

Target Details for TWIST2

Target: TWIST2 (Twist Homolog 2 (TWIST2))

Alternative Name: TWIST2 (TWIST2 Products)

Synonyms: TWIST2 antibody, DERMO1 antibody, FFDD3 antibody, SETLSS antibody, bHLHa39 antibody, Dermo1 antibody, CDERMO-1 antibody, twist family bHLH transcription factor 2 antibody, twist basic helix-loop-helix transcription factor 2 antibody, TWIST2 antibody, Twist2 antibody

Background: Full Gene Name: twist homolog 2 (Drosophila)
Synonyms: DERMO1,MGC117334,bHLHa39

Gene ID: 117581

Pathways: Chromatin Binding