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Recombinant Complement Receptor 1 & 2 antibody

Reactivity: Mouse FACS, IP, WB, BR, CoSt, IHC (fro) Host: Rat Monoclonal 7G6 unconjugated Recombinant Antibody
Catalog No. ABIN5668016
  • Target
    Complement Receptor 1 & 2
    Antibody Type
    Recombinant Antibody
    Reactivity
    Mouse
    Host
    • 1
    • 1
    Rat
    Clonality
    • 1
    • 1
    Monoclonal
    Conjugate
    • 2
    Un-conjugated
    Application
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Flow Cytometry (FACS), Immunoprecipitation (IP), Western Blotting (WB), Blocking Reagent (BR), Co-Stimulation (CoSt), Immunohistochemistry (Frozen Sections) (IHC (fro))
    Specificity
    Recognises an epitope shared by 145-150 kDa and 190 kDa complement receptor proteins, originally designated CR2 (CD21) and CR1 (CD35).
    Characteristics

    OriginalSpeciesName: Rat

    OriginalFormat: IgG2b

    Purification
    Purified antibody.
    Immunogen
    Purified Mouse CR1.
    Clone
    7G6
    Isotype
    IgG2b kappa
  • Application Notes
    This antibody binds mouse complement receptors CR1 and CR2, functionally blocking CR2 leading to suppression of a normal antibody immune response (see Heyman et al. 1990, PMID: 1695671)
    Restrictions
    For Research Use only
  • Buffer
    PBS with 0.02 % Proclin 300.
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.
  • Target
    Complement Receptor 1 & 2
    Background
    CD21 & CD35
    UniProt
    P19070, P17927
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