Recombinant Complement Receptor 1 & 2 antibody
Reactivity: Mouse
FACS, IP, WB, BR, CoSt, IHC (fro)
Host: Rabbit
Chimeric
7G6
unconjugated
Recombinant Antibody
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- Target
- Complement Receptor 1 & 2
- Antibody Type
- Recombinant Antibody
- Reactivity
- Mouse
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Host
- Rabbit
-
Clonality
- Chimeric
-
Conjugate
- Un-conjugated
-
Application
- Flow Cytometry (FACS), Immunoprecipitation (IP), Western Blotting (WB), Blocking Reagent (BR), Co-Stimulation (CoSt), Immunohistochemistry (Frozen Sections) (IHC (fro))
- Specificity
- Recognises an epitope shared by 145-150 kDa and 190 kDa complement receptor proteins, originally designated CR2 (CD21) and CR1 (CD35).
- Characteristics
-
OriginalSpeciesName: Rat
OriginalFormat: IgG2b
- Purification
- Purified antibody.
- Immunogen
- Purified Mouse CR1.
- Clone
- 7G6
- Isotype
- IgG kappa
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- Application Notes
- This antibody binds mouse complement receptors CR1 and CR2, functionally blocking CR2 leading to suppression of a normal antibody immune response (see Heyman et al. 1990, PMID: 1695671)
- Comment
-
This chimeric rabbit antibody was made using the variable domain sequences of the original Rat IgG2b format, for improved compatibility with existing reagents, assays and techniques.
- Restrictions
- For Research Use only
-
- Buffer
- PBS with 0.02 % Proclin 300.
- Preservative
- ProClin
- Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C,-20 °C
- Storage Comment
- Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.
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