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Recombinant p53 antibody (AA 371-380)

TP53 Reactivity: Human, Mouse, Rat, Monkey, Rabbit WB, ELISA, IF, IHC (p), IP, IHC (fro), in vivo Host: Mouse Monoclonal PAb421 unconjugated Recombinant Antibody
Catalog No. ABIN5668085
  • Target See all p53 (TP53) Antibodies
    p53 (TP53) (Tumor Protein P53 (TP53))
    Antibody Type
    Recombinant Antibody
    Binding Specificity
    • 41
    • 39
    • 37
    • 31
    • 29
    • 28
    • 26
    • 26
    • 24
    • 22
    • 21
    • 19
    • 19
    • 19
    • 18
    • 18
    • 16
    • 13
    • 12
    • 9
    • 9
    • 8
    • 8
    • 7
    • 7
    • 6
    • 6
    • 6
    • 6
    • 6
    • 6
    • 5
    • 5
    • 5
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    AA 371-380
    Reactivity
    • 804
    • 257
    • 210
    • 100
    • 46
    • 33
    • 30
    • 18
    • 10
    • 10
    • 8
    • 6
    • 6
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Human, Mouse, Rat, Monkey, Rabbit
    Host
    • 618
    • 204
    • 5
    • 2
    • 2
    Mouse
    Clonality
    • 568
    • 262
    • 1
    Monoclonal
    Conjugate
    • 461
    • 38
    • 31
    • 20
    • 17
    • 14
    • 14
    • 14
    • 14
    • 14
    • 14
    • 14
    • 14
    • 14
    • 12
    • 11
    • 11
    • 11
    • 11
    • 11
    • 11
    • 11
    • 10
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This p53 antibody is un-conjugated
    Application
    • 633
    • 282
    • 227
    • 192
    • 183
    • 143
    • 129
    • 122
    • 97
    • 61
    • 54
    • 32
    • 20
    • 17
    • 12
    • 10
    • 9
    • 8
    • 6
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP), Immunohistochemistry (Frozen Sections) (IHC (fro)), In vivo Studies (in vivo)
    Purpose
    Anti-p53 [PAb421], Mouse IgG2a, kappa
    Specificity
    Recognises the mammalian mutant and wild-type p53 protein and reacts with an epitope between amino acid residues 370 and 378 (near the C-terminus of the protein), corresponding to the sequence "KKGQSTSRHK".
    Cross-Reactivity
    Monkey, Mouse, Rabbit, Rat
    Characteristics

    Original Species of Ab: Mouse

    Original Format of Ab: IgG2a

    Purification
    Protein A affinity purified
    Immunogen
    Synthetic peptide corresponding to aa 371-380 of human p53.
    Clone
    PAb421
    Isotype
    IgG2a kappa
    Top Product
    Discover our top product TP53 Primary Antibody
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Concentration
    1 mg/mL
    Buffer
    PBS with 0.02 % Proclin 300.
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.
  • Target
    p53 (TP53) (Tumor Protein P53 (TP53))
    Alternative Name
    p53 (TP53 Products)
    Background
    Tumor suppressor p53, Cellular tumor antigen p53
    UniProt
    P04637
    Pathways
    p53 Signaling, MAPK Signaling, PI3K-Akt Signaling, Apoptosis, AMPK Signaling, Chromatin Binding, ER-Nucleus Signaling, Positive Regulation of Endopeptidase Activity, Hepatitis C, Protein targeting to Nucleus, Autophagy, Warburg Effect
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