Recombinant p53 antibody (AA 371-380)
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- Target See all p53 (TP53) Antibodies
- p53 (TP53) (Tumor Protein P53 (TP53))
- Antibody Type
- Recombinant Antibody
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Binding Specificity
- AA 371-380
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Reactivity
- Human, Mouse, Rat, Monkey, Rabbit
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This p53 antibody is un-conjugated
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Application
- Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP), Immunohistochemistry (Frozen Sections) (IHC (fro)), In vivo Studies (in vivo)
- Purpose
- Anti-p53 [PAb421], Mouse IgG2a, kappa
- Specificity
- Recognises the mammalian mutant and wild-type p53 protein and reacts with an epitope between amino acid residues 370 and 378 (near the C-terminus of the protein), corresponding to the sequence "KKGQSTSRHK".
- Cross-Reactivity
- Monkey, Mouse, Rabbit, Rat
- Characteristics
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Original Species of Ab: Mouse
Original Format of Ab: IgG2a
- Purification
- Protein A affinity purified
- Immunogen
- Synthetic peptide corresponding to aa 371-380 of human p53.
- Clone
- PAb421
- Isotype
- IgG2a kappa
- Top Product
- Discover our top product TP53 Primary Antibody
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Concentration
- 1 mg/mL
- Buffer
- PBS with 0.02 % Proclin 300.
- Preservative
- ProClin
- Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C,-20 °C
- Storage Comment
- Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.
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- Target
- p53 (TP53) (Tumor Protein P53 (TP53))
- Alternative Name
- p53 (TP53 Products)
- Background
- Tumor suppressor p53, Cellular tumor antigen p53
- UniProt
- P04637
- Pathways
- p53 Signaling, MAPK Signaling, PI3K-Akt Signaling, Apoptosis, AMPK Signaling, Chromatin Binding, ER-Nucleus Signaling, Positive Regulation of Endopeptidase Activity, Hepatitis C, Protein targeting to Nucleus, Autophagy, Warburg Effect
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