Recombinant IL-4 antibody

Catalog No. ABIN5668088

The Rabbit Chimeric anti-IL-4 antibody (Clone 11B11) (ABIN5668088) specifically detects IL-4 in ELISA, IHC, FACS and in vivo. The antibody is reactive with Mouse samples.

Quick Overview for Recombinant IL-4 antibody (ABIN5668088)

Target: IL-4 (IL4) (Interleukin 4 (IL4))

Antibody Type: Recombinant Antibody

Reactivity: Mouse

Host: Rabbit

Clonality: Chimeric

Conjugate: This IL-4 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS), In vivo Studies (in vivo)

Clone: 11B11

Product Details anti-IL-4 Antibody

Purpose: Anti-IL-4 [11B11], Rabbit IgG, kappa

Specificity: Binds to a core functional region of murine IL-4, which prevents this cytokine from interacting with its cognate receptor (Yao et al., 2006 PMID: 16361318).

Characteristics: This chimeric rabbit antibody was made using the variable domain sequences of the original Rat IgG1 format, for improved compatibility with existing reagents, assays and techniques.

Purification: Protein A affinity purified

Immunogen: BSF-1 / IL-4 purified from serum-free supernatants of cultured EL-4 cells (a C57BL/6 thymoma) induced with 4beta-phorbol 12beta-myristate 12alpha-acetate for 48h.

Isotype: IgG, kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

OriginalSpeciesName: Rat

OriginalFormat: IgG1

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % Proclin 300.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.

Target Details for IL-4

Target: IL-4 (IL4) (Interleukin 4 (IL4))

Alternative Name: IL-4

Background: Interleukin-4, Il4, Il-4, B-cell IgG differentiation factor, B-cell growth factor 1, B-cell stimulatory factor 1, BSF-1

UniProt: P07750

Pathways: JAK-STAT Signaling, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Proton Transport, Activated T Cell Proliferation