Recombinant MUC1 antibody

Catalog No. ABIN5668229

This Rabbit Chimeric antibody specifically detects MUC1 in IHC, ELISA and BI. It exhibits reactivity toward Human.

Quick Overview for Recombinant MUC1 antibody (ABIN5668229)

Target: MUC1 (Mucin 1 (MUC1))

Antibody Type: Recombinant Antibody

Reactivity: Human

Host: Rabbit

Clonality: Chimeric

Conjugate: This MUC1 antibody is un-conjugated

Application: Immunohistochemistry (IHC), ELISA, BioImaging (BI)

Clone: HMFG2

Product Details anti-MUC1 Antibody

Purpose: Anti-MUC1 [HMFG2], Rabbit IgG, lambda

Specificity: This antibody recognises MUC1, a tumor associated antigen which is expressed in >90 % ovarian carcinomas. This antigen is a high molecular weight (M, 80,000-200,000) glycoprotein.

Characteristics:

Original Species of Ab: Mouse

Original Format of Ab: IgG1

Purification: Protein A affinity purified

Immunogen: High-MW glycoprotein of the human milk fat globule.

Isotype: IgG lambda

Application Details

Application Notes: This antibody binds to MUC1, an antigen widely expressed on breast cancer cells. This antibody antibodies react strongly with malignant epithelial cells but not with normal mesothelial or endothelial cells.

Comment:

This chimeric rabbit antibody was made using the variable domain sequences of the original Mouse IgG1 format, for improved compatibility with existing reagents, assays and techniques.

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % Proclin 300.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.

Target Details for MUC1

Target: MUC1 (Mucin 1 (MUC1))

Alternative Name: MUC1

Background: Muc-1

UniProt: P15941

Pathways: Negative Regulation of intrinsic apoptotic Signaling