RASSF5 antibody (N-Term)

Catalog No. ABIN5672597

This anti-RASSF5 antibody is a Rabbit Polyclonal antibody detecting RASSF5 in WB. Suitable for Human.

Quick Overview for RASSF5 antibody (N-Term) (ABIN5672597)

Target: RASSF5 (Ras Association (RalGDS/AF-6) Domain Family Member 5 (RASSF5))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RASSF5 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-RASSF5 Antibody

Binding Specificity: N-Term

Sequence: IGQRPYPLLL DPEPPRYLQS LSGPELPPPP PDRSSRLCVP APLSTAPGAR

Purification: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human RASSF5

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for RASSF5

Target: RASSF5 (Ras Association (RalGDS/AF-6) Domain Family Member 5 (RASSF5))

Alternative Name: RASSF5

Background: This gene is a member of the Ras association domain family. It functions as a tumor suppressor, and is inactivated in a variety of cancers. The encoded protein localizes to centrosomes and microtubules, and associates with the GTP-activated forms of Ras, Rap1, and several other Ras-like small GTPases. The protein regulates lymphocyte adhesion and suppresses cell growth in response to activated Rap1 or Ras. Multiple transcript variants encoding different isoforms have been found for this gene.

Alias Symbols: RAPL, Maxp1, NORE1, NORE1A, NORE1B, RASSF3

Protein Size: 418

Gene ID: 83593

NCBI Accession: NM_182663, NP_872604

UniProt: Q8WWW0

Pathways: TCR Signaling