RAB11FIP2 antibody (AA 331-430)

Catalog No. ABIN5675671

The Rabbit Polyclonal anti-RAB11FIP2 antibody is suitable to detect RAB11FIP2 in samples from Human and Mouse. It has been validated for WB and ELISA.

Quick Overview for RAB11FIP2 antibody (AA 331-430) (ABIN5675671)

Target: RAB11FIP2 (RAB11 Family Interacting Protein 2 (Class I) (RAB11FIP2))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RAB11FIP2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-RAB11FIP2 Antibody

Binding Specificity: AA 331-430

Cross-Reactivity: Human, Mouse

Predicted Reactivity: Rat,Dog,Cow,Pig,Horse,Chicken,Cat,Rabbit,Guinea Pig

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human RAB11-FIP2

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for RAB11FIP2

Target: RAB11FIP2 (RAB11 Family Interacting Protein 2 (Class I) (RAB11FIP2))

Alternative Name: RAB11-FIP2

Background:

Synonyms: RAB11FIP2,KIAA0941, NRip11, RAB11 family interacting protein 2 (class I), Rab11 family-interacting protein 2, RAB11 FIP2 long isoform, Rab11-FIP2, RFIP2, RFIP2_HUMAN.

Background: A Rab11 effector binding preferentially phosphatidylinositol 3,4,5-trisphosphate (PtdInsP3) and phosphatidic acid (PA) and acting in the regulation of the transport of vesicles from the endosomal recycling compartment (ERC) to the plasma membrane. Involved in insulin granule exocytosis. Also involved in receptor-mediated endocytosis and membrane trafficking of recycling endosomes, probably originating from clathrin-coated vesicles. Required in a complex with MYO5B and RAB11 for the transport of NPC1L1 to the plasma membrane. Also acts as a regulator of cell polarity.

Gene ID: 22841

UniProt: Q7L804

Pathways: Hormone Transport, Carbohydrate Homeostasis