RAB11FIP2 antibody (AA 310-390)

Catalog No. ABIN7220550

The Rabbit Polyclonal anti-RAB11FIP2 antibody is suitable to detect RAB11FIP2 in samples from Human and Mouse. It has been validated for WB, ELISA and IHC.

Quick Overview for RAB11FIP2 antibody (AA 310-390) (ABIN7220550)

Target: RAB11FIP2 (RAB11 Family Interacting Protein 2 (Class I) (RAB11FIP2))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RAB11FIP2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Product Details anti-RAB11FIP2 Antibody

Binding Specificity: AA 310-390

Purpose: Rabbit Anti-Rab11-FIP2 Polyclonal Antibody

Specificity: Rab11-FIP2 Polyclonal Antibody detects endogenous levels of Rab11-FIP2 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the Internal region of human Rab11-FIP2 at AA range: 310-390

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,IHC 1:50-300,ELISA 1:2000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for RAB11FIP2

Target: RAB11FIP2 (RAB11 Family Interacting Protein 2 (Class I) (RAB11FIP2))

Alternative Name: Rab11-FIP2

Background: RAB11FIP2, KIAA0941, Rab11 family-interacting protein 2, Rab11-FIP2, NRip11A Rab11 effector binding preferentially phosphatidylinositol 3,4,5-trisphosphate (PtdInsP3) and phosphatidic acid (PA) and acting in the regulation of the transport of vesicles from the endosomal recycling compartment (ERC) to the plasma membrane. Involved in insulin granule exocytosis. Also involved in receptor-mediated endocytosis and membrane trafficking of recycling endosomes, probably originating from clathrin-coated vesicles. Required in a complex with MYO5B and RAB11 for the transport of NPC1L1 to the plasma membrane. Also acts as a regulator of cell polarity.

Molecular Weight: 58kD

Gene ID: 22841

UniProt: Q7L804

Pathways: Hormone Transport, Carbohydrate Homeostasis