Caspase 1 p20 antibody (AA 181-280)

Catalog No. ABIN5675787

This Rabbit Polyclonal antibody specifically detects Caspase 1 p20 in WB, FACS, IF (cc), IF (p), IHC (fro) and IHC (p). It exhibits reactivity toward Mouse.It has been mentioned in 1 publication

Quick Overview for Caspase 1 p20 antibody (AA 181-280) (ABIN5675787)

Target: Caspase 1 p20

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Caspase 1 p20 antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-Caspase 1 p20 Antibody

Binding Specificity: AA 181-280

Purpose: Caspase-1 p20 Polyclonal Antibody

Cross-Reactivity: Human, Mouse, Rat

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from mouse Caspase-1 p20

Isotype: IgG

Application Details

Application Notes: WB(1:300-5000),

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

References for anti-Caspase 1 p20 antibody (ABIN5675787)

Wang, Gong, Cai, Jing, Yang, Yuan, Chen, Tian: "Knockout of Sirt2 alleviates traumatic brain injury in mice." in: Neural regeneration research, Vol. 18, Issue 2, pp. 350-356, (2023) (PubMed).

Target Details for Caspase 1 p20

Target: Caspase 1 p20

Alternative Name: Caspase-1 p20

Background:

Synonyms: Caspase-1, Casp1, CASP-1, Interleukin-1 beta convertase, IL-1BC, Interleukin-1 beta-converting enzyme, ICE, IL-1 beta-converting enzyme, p45, Casp1, Caspase-1 subunit p20, Il1bc

Background: Thiol protease that cleaves IL-1 beta between an Asp and an Ala, releasing the mature cytokine which is involved in a variety of inflammatory processes. Important for defense against pathogens. Cleaves and activates sterol regulatory element binding proteins (SREBPs). Can also promote apoptosis.

Gene ID: 12362

UniProt: P29452