Calretinin antibody

Catalog No. ABIN5680171

The Mouse Monoclonal anti-Calretinin antibody is suitable to detect Calretinin in samples from Human. It has been validated for WB, IHC (p) and IHC (fro).

Quick Overview for Calretinin antibody (ABIN5680171)

Target: Calretinin (CALB2) (Calbindin 2 (CALB2))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Calretinin antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Clone: 6B3

Product Details anti-Calretinin Antibody

Specificity: Calretinin, no cross-reaction with Calbindin and Calmodulin

Cross-Reactivity (Details): Human, Rat

Characteristics: The antibody is suitable for the detection of Calretinin in neurons and may be used as an aid in differential diagnosis of pleura-mesothelioma. This marker is frequently expressed in epitheloid mesothelioma, while occasionally it turns positive in sarcomatous mesothelioma and carcinoma. It was found to be negative in sarcoma (2,3) and in 90 % of adenocarcinoma. Calretinin is a Calcium-binding protein related to Calmodulin and Calbindin. It is found in groups of neurons of the brain cortex, in the retina and in the spinal cord (1). More recent studies show that it is a suitable marker for mesothelioma of the lung (2, 3, 4, 5). Calretinin, no cross-reaction with Calbindin and Calmodulin.

Purification: Antibody solution

Immunogen: Recombinant human Calretinin 22kDa

Isotype: Ig Fraction

Application Details

Application Notes: Improvement of staining with Unmasking Fluid G or Unmasking Fluid C ,Cerebral cortex, pleural mesothelioma,IHC(C, P), Immunoblotting,60 min at RT,(liquid conc.) 1:40-1:50

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: stabilizing phosphate buffer  pH 7.3. Contains 0.09 % sodium azide. The volume is sufficient for 200-500 immunohistochemical tests (100 μL working solution / test)

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Target Details for Calretinin

Target: Calretinin (CALB2) (Calbindin 2 (CALB2))

Alternative Name: Calretinin