Histone Cluster 2, H4a (HIST2H4A) (meLys20) antibody

Catalog No. ABIN5684092

The Mouse Monoclonal anti- antibody has been validated for WB, ELISA, FACS, IHC and ICC. It is suitable to detect in samples from Human.

Quick Overview for Histone Cluster 2, H4a (HIST2H4A) (meLys20) antibody (ABIN5684092)

Target: Histone Cluster 2, H4a (HIST2H4A)

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: Un-conjugated

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunohistochemistry (IHC), Immunocytochemistry (ICC)

Clone: 3E7H2

Product Details

Binding Specificity: meLys20

Purpose: HIST2H4A (20Me) Antibody

Purification: Purified antibody

Immunogen: Synthesized peptide of human HIST2H4A ( AA: GGAKRHRK(Me)VLRDNIQ ).

Isotype: IgG1

Application Details

Application Notes:

ELISA: 1/10000

FCM: 1/200 - 1/400

ICC: 1/200 - 1/1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Target Details

Target: Histone Cluster 2, H4a (HIST2H4A)

Alternative Name: HIST2H4A

Background: Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. This structure consists of approximately 146 bp of DNA wrapped around a nucleosome, an octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a member of the histone H4 family. Transcripts from this gene lack polyA tails, instead, they contain a palindromic termination element. This gene is found in a histone cluster on chromosome 1. This gene is one of four histone genes in the cluster that are duplicated, this record represents the centromeric copy.

Molecular Weight: 11.4 kDa

UniProt: P62805

Pathways: Telomere Maintenance