CD226 antibody (AA 19-254)

Catalog No. ABIN5684118

Product Details anti-CD226 Antibody

Target: CD226

Binding Specificity: AA 19-254

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CD226 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Neutralization (Neut)

Purification: purified

Immunogen: Purified recombinant fragment of human CD226 (AA: extra 19-254) expressed in E. coli.

Clone: 5E3A8

Isotype: IgG1

Application Details

Application Notes: ELISA: 1:10000, WB: 1:500 - 1:2000, ICC: N/A, FCM: N/A, IHC: N/A

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C/-20 °C

Storage Comment: 4°C, -20°C for long term storage

Target Details for CD226

Target: CD226

Alternative Name: CD226 (CD226 Products)

Synonyms: CD226 antibody, cd226 antibody, zgc:158817 antibody, BC051526 antibody, DNAM-1 antibody, DNAM1 antibody, Pta1 antibody, TLiSA1 antibody, PTA1 antibody, CD226 molecule antibody, CD226 antigen antibody, CD226 antibody, cd226 antibody, Cd226 antibody

Background:

Description: This gene encodes a glycoprotein expressed on the surface of NK cells, platelets, monocytes and a subset of T cells. It is a member of the Ig-superfamily containing 2 Ig-like domains of the V-set. The protein mediates cellular adhesion of platelets and megakaryocytic cells to vascular endothelial cells. The protein also plays a role in megakaryocytic cell maturation. Alternative splicing results in multiple transcript variants.

Aliases: PTA1, DNAM1, DNAM-1, TLiSA1

Molecular Weight: 38.6 kDa

Gene ID: 10666

HGNC: 3673

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Cancer Immune Checkpoints