CD226 antibody (AA 19-247)

Catalog No. ABIN7092896

The Rabbit Monoclonal anti-CD226 antibody (Clone DM95) (ABIN7092896) specifically detects CD226 in FACS and ELISA. The antibody is reactive with Human samples.

Quick Overview for CD226 antibody (AA 19-247) (ABIN7092896)

Target: CD226

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This CD226 antibody is un-conjugated

Application: Flow Cytometry (FACS), ELISA

Clone: DM95

Product Details anti-CD226 Antibody

Binding Specificity: AA 19-247

Purpose: Anti-DNAM-1 antibody(DM95), Rabbit mAb

Purification: Purified from cell culture supernatant by affinity chromatography

Immunogen: Recombinant human DNAM-1 (Glu19-Asn247) (ABIN6961117) produced by using human HEK293 cells

Isotype: IgG

Application Details

Application Notes: ELISA 1:5000-10000, Flow Cyt 1:100

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Please see Certificate of Analysis for specific instructions of reconstitution.

Buffer: Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.

Storage: -20 °C,-80 °C

Storage Comment: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Expiry Date: 12 months

Target Details for CD226

Target: CD226

Alternative Name: DNAM1

Background: Synonyms:DNAM1, CD226, PTA1
Description:This gene encodes a glycoprotein expressed on the surface of NK cells, platelets, monocytes and a subset of T cells. It is a member of the Ig-superfamily containing 2 Ig-like domains of the V-set. The protein mediates cellular adhesion of platelets and megakaryocytic cells to vascular endothelial cells. The protein also plays a role in megakaryocytic cell maturation. Alternative splicing results in multiple transcript variants.

Molecular Weight: 38.6kDa

Gene ID: 10666

UniProt: Q15762

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Cancer Immune Checkpoints